AutismKB 2.0

Annotation Details for AP4M1


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Basic Information Top
Gene Symbol:AP4M1 ( CPSQ3,MU-4,MU-ARP2 )
Gene Full Name: adaptor-related protein complex 4, mu 1 subunit
Band: 7q22.1
Quick LinksEntrez ID:9179; OMIM: 602296; Uniprot ID:AP4M1_HUMAN; ENSEMBL ID: ENSG00000221838; HGNC ID: 574
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000138TAS-Golgi trans cisterna10066790
GO:0005802IDA-trans-Golgi network20230749
GO:0005829IEA-cytosol-
GO:0030119TAS-AP-type membrane coat adaptor complex10066790
GO:0030131IEA-clathrin adaptor complex-
GO:0031904TAS-endosome lumen-
GO:0032588TAS-trans-Golgi network membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005215TAS-transporter activity10066790
GO:0005515IPI-protein binding25416956
GO ID Evidence Qualifier GO_term References
GO:0006886IMP-intracellular protein transport20230749
GO:0006895IMP-Golgi to endosome transport20230749
GO:0016192TAS-vesicle-mediated transport10066790
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AP4M1ARF111461611707398 Two-hybrid
AP4M1ARF110687011707398 Two-hybrid
AP4E1AP4M111461610436028 Affinity Capture-Western
AP4E1AP4M111699910436028 Affinity Capture-Western
AP4B1AP4M111461610436028 Affinity Capture-Western; Two-hybrid
AP4B1AP4M111594310436028 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1337063
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018