AutismKB 2.0

Annotation Details for BUB3


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Basic Information Top
Gene Symbol:BUB3 ( BUB3L,hBUB3 )
Gene Full Name: budding uninhibited by benzimidazoles 3 homolog (yeast)
Band: 10q26.13
Quick LinksEntrez ID:9184; OMIM: 603719; Uniprot ID:BUB3_HUMAN; ENSEMBL ID: ENSG00000154473; HGNC ID: 1151
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000776IDA-kinetochore9660858
GO:0000777IEA-condensed chromosome kinetochore-
GO:0005654IDA-nucleoplasm-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding9660858
GO ID Evidence Qualifier GO_term References
GO:0000070IEA-mitotic sister chromatid segregation-
GO:0007062TAS-sister chromatid cohesion-
GO:0008608IDA-attachment of spindle microtubules to kinetochore18199686
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0042787TAS-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0051301IEA-cell division-
GO:0051321IEA-meiotic cell cycle-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0051983IEA-regulation of chromosome segregation-
GO:0071173IDA-spindle assembly checkpoint15525512
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BUB3PARP111462112011073 Affinity Capture-Western
BUB3PARP110665212011073 Affinity Capture-Western
BUB3APC11462111283619 Affinity Capture-Western
BUB3APC10682111283619 Affinity Capture-Western
BUB3BUB1B1146219660858 11535616 12419313 Affinity Capture-Western; Co-purification; Two-hybrid
BUB3BUB1B1071669660858 11535616 12419313 Affinity Capture-Western; Co-purification; Two-hybrid
BUB3HDAC111462115388328 Affinity Capture-Western; Co-purification
BUB3HDAC110931515388328 Affinity Capture-Western; Co-purification
BUB3HDAC211462115388328 Affinity Capture-Western; Co-purification
BUB3HDAC210931615388328 Affinity Capture-Western; Co-purification
BUB3USP711462119615732 Affinity Capture-MS
BUB3USP711362219615732 Affinity Capture-MS
BUB3USP1111462119615732 Affinity Capture-MS
BUB3USP1111386619615732 Affinity Capture-MS
WBP4BUB311636316055720 Affinity Capture-MS
WBP4BUB311462116055720 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1343463
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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