AutismKB 2.0

Annotation Details for CD247


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Basic Information Top
Gene Symbol:CD247 ( CD3-ZETA,CD3H,CD3Q,CD3Z,T3Z,TCRZ )
Gene Full Name: CD247 molecule
Band: 1q24.2
Quick LinksEntrez ID:919; OMIM: 186780; Uniprot ID:CD3Z_HUMAN; ENSEMBL ID: ENSG00000198821; HGNC ID: 1677
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm11390434
GO:0005886IDA-plasma membrane1390434
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0042101IDA-T cell receptor complex8176201
GO:0042105IEA-alpha-beta T cell receptor complex-
GO ID Evidence Qualifier GO_term References
GO:0004888IEA-transmembrane signaling receptor activity-
GO:0005515IPI-protein binding7509083
GO:0042802IPI-identical protein binding17055436
GO:0042803IMP-protein homodimerization activity8681956
GO:0042803NAS-protein homodimerization activity12110186
GO:1990782IPI-protein tyrosine kinase binding8681956
GO ID Evidence Qualifier GO_term References
GO:0016032IEA-viral process-
GO:0031295TAS-T cell costimulation-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0050690TAS-regulation of defense response to virus by virus-
GO:0050776TAS-regulation of immune response-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051289IMP-protein homotetramerization14967045
GO:0070207IMP-protein homotrimerization14967045
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPRCCD2471073577526385 Reconstituted Complex
PTPRCCD2471117527526385 Reconstituted Complex
ZAP70CD2471073577737297 Affinity Capture-Western
ZAP70CD2471133677737297 Affinity Capture-Western
ATXN2CD2471073579575182 Affinity Capture-Western
ATXN2CD2471122189575182 Affinity Capture-Western
NCR1CD2471073579625766 Affinity Capture-Western
NCR1CD2471148289625766 Affinity Capture-Western
STAT5ACD2471073579880255 Affinity Capture-Western
STAT5ACD2471126539880255 Affinity Capture-Western
STAT5BCD2471126549880255 Affinity Capture-Western
STAT5BCD2471073579880255 Affinity Capture-Western
SLACD24710735710449770 Affinity Capture-Western
SLACD24711239410449770 Affinity Capture-Western
JAK3CD24710735711349123 Affinity Capture-Western; Reconstituted Complex
JAK3CD24710992111349123 Affinity Capture-Western; Reconstituted Complex
TRAT1CD24710735711390434 Affinity Capture-Western
TRAT1CD24711915411390434 Affinity Capture-Western
GAB2CD24710735711572860 Affinity Capture-Western
GAB2CD24711518111572860 Affinity Capture-Western
SLA2CD24710735711891219 Affinity Capture-Western
SLA2CD24712392811891219 Affinity Capture-Western
DOCK2CD24710735712176041 Affinity Capture-Western
DOCK2CD24710812912176041 Affinity Capture-Western
UNC119CD24710735714757743 Affinity Capture-Western; Reconstituted Complex
UNC119CD24711454814757743 Affinity Capture-Western; Reconstituted Complex
TUBA1BCD24710735715084271 Affinity Capture-Western
TUBA1BCD24711565115084271 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88334
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061130-4'