AutismKB 2.0

Annotation Details for LRRFIP1


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Basic Information Top
Gene Symbol:LRRFIP1 ( FLAP-1,FLIIAP1,GCF-2,GCF2,HUFI-1,MGC10947,MGC119738,MGC119739,TRIP )
Gene Full Name: leucine rich repeat (in FLII) interacting protein 1
Band: 2q37.3
Quick LinksEntrez ID:9208; OMIM: 603256; Uniprot ID:LRRF1_HUMAN; ENSEMBL ID: ENSG00000124831; HGNC ID: 6702
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005634NAS-nucleus9705290
GO:0005737TAS-cytoplasm9671805
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005856TAS-cytoskeleton9671805
GO:0005886IDA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0003677IDA-DNA binding23099021
GO:0003725TAS-double-stranded RNA binding9671805
GO:0005515IPI-protein binding9671805
GO:0042803IDA-protein homodimerization activity23099021
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter9705290
GO:0008150ND-biological_process-
GO:0032481TAS-positive regulation of type I interferon production-
GO:0045892NAS-negative regulation of transcription, DNA-templated9705290
GO:0051092IEA-positive regulation of NF-kappaB transcription factor activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LRRFIP1FLII1146429525888 10366446 19265123 Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
LRRFIP1FLII1086039525888 10366446 19265123 Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
LRRFIP1MYD8811464219265123 Affinity Capture-Western
LRRFIP1MYD8811070019265123 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-99'