AutismKB 2.0

Annotation Details for DLG5


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Basic Information Top
Gene Symbol:DLG5 ( KIAA0583,LP-DLG,P-DLG5,PDLG )
Gene Full Name: discs, large homolog 5 (Drosophila)
Band: 10q22.3
Quick LinksEntrez ID:9231; OMIM: 604090; Uniprot ID:DLG5_HUMAN; ENSEMBL ID: ENSG00000151208; HGNC ID: 2904
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm9738934
GO:0005886IEA-plasma membrane-
GO:0005913IEA-cell-cell adherens junction-
GO:0014069ISS-postsynaptic density-
GO:0030054IDA-cell junction28169360
GO:0036064ISS-ciliary basal body-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding23624079
GO:0008013IDA-beta-catenin binding12657639
GO:0008092IDA-cytoskeletal protein binding12657639
GO:0030159NAS-receptor signaling complex scaffold activity12353226
GO ID Evidence Qualifier GO_term References
GO:0001837IMP-epithelial to mesenchymal transition28169360
GO:0006461IEA-protein complex assembly-
GO:0007165TAS-signal transduction9738934
GO:0008285TAS-negative regulation of cell proliferation9738934
GO:0016337NAS-single organismal cell-cell adhesion12353226
GO:0030011IMP-maintenance of cell polarity28169360
GO:0030336IMP-negative regulation of cell migration28169360
GO:0030859IEA-polarized epithelial cell differentiation-
GO:0030901IEA-midbrain development-
GO:0035331IMP-negative regulation of hippo signaling28087714
GO:0035332IMP-positive regulation of hippo signaling28169360
GO:0035556NAS-intracellular signal transduction12353226
GO:0042130IMP-negative regulation of T cell proliferation28169360
GO:0042981IEA-regulation of apoptotic process-
GO:0045176IEA-apical protein localization-
GO:0045186IEA-zonula adherens assembly-
GO:0045197IEA-establishment or maintenance of epithelial cell apical/basal polarity-
GO:0045880ISS-positive regulation of smoothened signaling pathway-
GO:0051965ISS-positive regulation of synapse assembly-
GO:0060441IEA-epithelial tube branching involved in lung morphogenesis-
GO:0060999ISS-positive regulation of dendritic spine development-
GO:0071896IEA-protein localization to adherens junction-
GO:0072205IEA-metanephric collecting duct development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DLG5CD8111466216169070 Two-hybrid
DLG5CD8110741316169070 Two-hybrid
DLG5CTNNB111466212657639 Affinity Capture-Western
DLG5CTNNB110788012657639 Affinity Capture-Western
DLG5DLST10808716169070 Two-hybrid
DLG5DLST11466216169070 Two-hybrid
DLG5PFN111466216169070 Two-hybrid
DLG5PFN111123716169070 Two-hybrid
DLG5TERF111466216169070 Two-hybrid
DLG5TERF111287216169070 Two-hybrid
SORBS3DLG511466212657639 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SORBS3DLG511547512657639 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BTBD10DLG511466216169070 Two-hybrid
BTBD10DLG512400716169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1918478
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3149'