AutismKB 2.0

Annotation Details for CD8A


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Basic Information Top
Gene Symbol:CD8A ( CD8,Leu2,MAL,p32 )
Gene Full Name: CD8a molecule
Band: 2p11.2
Quick LinksEntrez ID:925; OMIM: 186910; Uniprot ID:CD8A_HUMAN; ENSEMBL ID: ENSG00000153563; HGNC ID: 1706
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IEA-extracellular region-
GO:0005886TAS-plasma membrane-
GO:0005887NAS-integral component of plasma membrane2496167
GO:0009897IDA-external side of plasma membrane17213291
GO:0042101NAS-T cell receptor complex11131152
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding2470098
GO:0015026NAS-coreceptor activity11131152
GO:0019901IEA-protein kinase binding-
GO:0042288NAS-MHC class I protein binding11131152
GO:0042803IEA-protein homodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0002456IBA-T cell mediated immunity-
GO:0006955NAS-immune response11131152
GO:0007166IBA-cell surface receptor signaling pathway-
GO:0007169NAS-transmembrane receptor protein tyrosine kinase signaling pathway9830036
GO:0019882NAS-antigen processing and presentation2496167
GO:0042110NAS-T cell activation9830036
GO:0045065IBA-cytotoxic T cell differentiation-
GO:0050776TAS-regulation of immune response-
GO:0050850IEA-positive regulation of calcium-mediated signaling-
GO:0051607IEA-defense response to virus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CD8ACD3D10736312215456 Affinity Capture-Western; FRET
CD8ACD3D10735312215456 Affinity Capture-Western; FRET
CD59CD8A1073631377690 Reconstituted Complex
CD59CD8A1074041377690 Reconstituted Complex
PTPRCCD8A1073631834739 FRET
PTPRCCD8A1117521834739 FRET
HLA-GCD8A1073631908512 10809759 Reconstituted Complex
HLA-GCD8A1093801908512 10809759 Reconstituted Complex
CD8ACD8A1073638127870 9550407 Co-crystal Structure; Co-localization
HLA-ACD8A1073639177355 10809759 Co-crystal Structure; Reconstituted Complex
HLA-ACD8A1093509177355 10809759 Co-crystal Structure; Reconstituted Complex
CD8BCD8A1073639550407 Co-localization
CD8BCD8A1073649550407 Co-localization
HLA-BCD8A10736310809759 Reconstituted Complex
HLA-BCD8A10935110809759 Reconstituted Complex
HLA-CCD8A10736310809759 Reconstituted Complex
HLA-CCD8A10935210809759 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88346
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060210-2'