AutismKB 2.0

Annotation Details for GPR56


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Basic Information Top
Gene Symbol:GPR56 ( BFPP,DKFZp781L1398,TM7LN4,TM7XN1 )
Gene Full Name: G protein-coupled receptor 56
Band: 16q13
Quick LinksEntrez ID:9289; OMIM: 604110; Uniprot ID:GPR56_HUMAN; ENSEMBL ID: ENSG00000205336; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005887TAS-integral component of plasma membrane10049584
GO:0016021TAS-integral component of membrane15004227
GO:0045121IEA-membrane raft-
GO:0070062IDA-extracellular exosome23376485
GO:0097451ISS-glial limiting end-foot-
GO ID Evidence Qualifier GO_term References
GO:0004930ISS-G-protein coupled receptor activity-
GO:0005518ISS-collagen binding-
GO:0008201IDA-heparin binding27068534
GO:0050840ISS-extracellular matrix binding-
GO ID Evidence Qualifier GO_term References
GO:0001525IDA-angiogenesis21724588
GO:0007155IDA-cell adhesion27068534
GO:0007166IEA-cell surface receptor signaling pathway-
GO:0007186IEA-G-protein coupled receptor signaling pathway-
GO:0007266IDA-Rho protein signal transduction21708946
GO:0007267TAS-cell-cell signaling10049584
GO:0007420IMP-brain development15044805
GO:0008285IDA-negative regulation of cell proliferation16757564
GO:0010573IDA-vascular endothelial growth factor production21724588
GO:0016477IDA-cell migration27068534
GO:0021796IEA-cerebral cortex regionalization-
GO:0021801ISS-cerebral cortex radial glia guided migration-
GO:0021819ISS-layer formation in cerebral cortex-
GO:0035025ISS-positive regulation of Rho protein signal transduction-
GO:0045785IDA-positive regulation of cell adhesion21349848
GO:0070528IDA-protein kinase C signaling21724588
GO:0072520IEA-seminiferous tubule development-
GO:2000179IEA-positive regulation of neural precursor cell proliferation-
GO:2001223ISS-negative regulation of neuron migration-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1340051
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018