Gene Symbol:	CD14 ( - )
Gene Full Name:	CD14 molecule
Band:	5q31.3
Quick Links	Entrez ID:929; OMIM: 158120; Uniprot ID:CD14_HUMAN; ENSEMBL ID: ENSG00000170458; HGNC ID: 1628
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005576	TAS	-	extracellular region	-
GO:0005615	IDA	-	extracellular space	16502470
GO:0005794	IDA	-	Golgi apparatus	16880211
GO:0005886	TAS	-	plasma membrane	-
GO:0010008	TAS	-	endosome membrane	-
GO:0030667	TAS	-	secretory granule membrane	-
GO:0031362	IDA	-	anchored component of external side of plasma membrane	3385210
GO:0045121	IDA	-	membrane raft	16880211
GO:0046696	IDA	-	lipopolysaccharide receptor complex	11274165
GO:0070062	IDA	-	extracellular exosome	19056867

GO ID	Evidence	Qualifier	GO_term	References
GO:0001530	IDA	-	lipopolysaccharide binding	12594207
GO:0001847	TAS	-	opsonin receptor activity	2402637
GO:0005515	IPI	-	protein binding	16880211
GO:0016019	TAS	-	peptidoglycan receptor activity	8798531
GO:0070891	IDA	-	lipoteichoic acid binding	12594207
GO:0071723	IDA	-	lipopeptide binding	15294986

GO ID	Evidence	Qualifier	GO_term	References
GO:0002224	TAS	-	toll-like receptor signaling pathway	-
GO:0002755	TAS	-	MyD88-dependent toll-like receptor signaling pathway	-
GO:0002756	TAS	-	MyD88-independent toll-like receptor signaling pathway	-
GO:0006898	IEA	-	receptor-mediated endocytosis	-
GO:0006909	TAS	-	phagocytosis	9548256
GO:0006915	TAS	-	apoptotic process	9548256
GO:0006954	IEA	-	inflammatory response	-
GO:0007166	TAS	-	cell surface receptor signaling pathway	8798531
GO:0007249	TAS	-	I-kappaB kinase/NF-kappaB signaling	-
GO:0009408	IEA	-	response to heat	-
GO:0031663	IEA	-	lipopolysaccharide-mediated signaling pathway	-
GO:0032026	IEA	-	response to magnesium ion	-
GO:0032481	IEA	-	positive regulation of type I interferon production	-
GO:0032729	ISS	-	positive regulation of interferon-gamma production	-
GO:0032760	IDA	-	positive regulation of tumor necrosis factor production	12594207
GO:0032760	IMP	-	positive regulation of tumor necrosis factor production	8612135
GO:0034128	TAS	-	negative regulation of MyD88-independent toll-like receptor signaling pathway	-
GO:0034142	ISS	-	toll-like receptor 4 signaling pathway	-
GO:0034142	TAS	-	toll-like receptor 4 signaling pathway	-
GO:0034612	IEA	-	response to tumor necrosis factor	-
GO:0035666	TAS	-	TRIF-dependent toll-like receptor signaling pathway	-
GO:0038123	TAS	-	toll-like receptor TLR1:TLR2 signaling pathway	-
GO:0038124	TAS	-	toll-like receptor TLR6:TLR2 signaling pathway	-
GO:0043312	TAS	-	neutrophil degranulation	-
GO:0045087	IEA	-	innate immune response	-
GO:0045471	IEA	-	response to ethanol	-
GO:0045807	IEA	-	positive regulation of endocytosis	-
GO:0051602	IEA	-	response to electrical stimulus	-
GO:0070266	TAS	-	necroptotic process	-
GO:0071219	IDA	-	cellular response to molecule of bacterial origin	15039339
GO:0071222	IDA	-	cellular response to lipopolysaccharide	12594207
GO:0071222	IMP	-	cellular response to lipopolysaccharide	8612135
GO:0071223	IDA	-	cellular response to lipoteichoic acid	12594207
GO:0071726	IDA	-	cellular response to diacyl bacterial lipopeptide	16880211
GO:0071727	IDA	-	cellular response to triacyl bacterial lipopeptide	16880211
GO:0097190	TAS	-	apoptotic signaling pathway	-
GO:1901224	IDA	-	positive regulation of NIK/NF-kappaB signaling	15294986
GO:2000484	IMP	-	positive regulation of interleukin-8 secretion	15039339

Gene Symbol	Interactant	Interaction ID	References	Description
LBP	CD14	110121	7583357 12417309	Co-purification; Reconstituted Complex
LBP	CD14	107367	7583357 12417309	Co-purification; Reconstituted Complex
TLR2	CD14	112952	10395652	Affinity Capture-Western
TLR2	CD14	107367	10395652	Affinity Capture-Western
LTF	CD14	107367	11083760	Reconstituted Complex
LTF	CD14	110235	11083760	Reconstituted Complex

AutismKB 2.0

Annotation Details for CD14

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Non-syndromic Genes

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