AutismKB 2.0

Annotation Details for CD19


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Basic Information Top
Gene Symbol:CD19 ( B4,MGC12802 )
Gene Full Name: CD19 molecule
Band: 16p11.2
Quick LinksEntrez ID:930; OMIM: 107265; Uniprot ID:CD19_HUMAN; ENSEMBL ID: ENSG00000177455; HGNC ID: 1633
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane2472450
GO:0009897IDA-external side of plasma membrane17213291
GO:0043234IDA-protein complex23071339
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0005057TAS-signal transducer activity, downstream of receptor1373518
GO:0005515IPI-protein binding19214191
GO:0046934TAS-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-
GO ID Evidence Qualifier GO_term References
GO:0006968TAS-cellular defense response1373518
GO:0007166TAS-cell surface receptor signaling pathway1714482
GO:0014066TAS-regulation of phosphatidylinositol 3-kinase signaling-
GO:0030449TAS-regulation of complement activation-
GO:0046854IEA-phosphatidylinositol phosphorylation-
GO:0048015TAS-phosphatidylinositol-mediated signaling-
GO:0050776TAS-regulation of immune response-
GO:0050853IBA-B cell receptor signaling pathway-
GO:0051281IEA-positive regulation of release of sequestered calcium ion into cytosol-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CD19CD91073669804823 Affinity Capture-Western
CD19CD91073689804823 Affinity Capture-Western
CR2CD191077711383329 9804823 Affinity Capture-Western
CR2CD191073681383329 9804823 Affinity Capture-Western
IFITM1CD191140911383329 Affinity Capture-Western
IFITM1CD191073681383329 Affinity Capture-Western
CD81CD191074131383329 7636191 9804823 Affinity Capture-Western
CD81CD191073681383329 7636191 9804823 Affinity Capture-Western
VAV1CD191132527528218 Affinity Capture-Western
VAV1CD191073687528218 Affinity Capture-Western
CD82CD191099357636191 9804823 Affinity Capture-Western
CD82CD191073687636191 9804823 Affinity Capture-Western
SYKCD191073689120258 Affinity Capture-Western
SYKCD191127179120258 Affinity Capture-Western
CD22CD191073689120258 Affinity Capture-Western
CD22CD191073719120258 Affinity Capture-Western
CD79ACD191074119120258 Affinity Capture-Western
CD79ACD191073689120258 Affinity Capture-Western
CD79BCD191074129120258 Affinity Capture-Western
CD79BCD191073689120258 Affinity Capture-Western
VAV2CD1911325311080163 Affinity Capture-Western; Reconstituted Complex
VAV2CD1910736811080163 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88319
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018