AutismKB 2.0

Annotation Details for COPS2


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Basic Information Top
Gene Symbol:COPS2 ( ALIEN,CSN2,SGN2,TRIP15 )
Gene Full Name: COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
Band: 15q21.2
Quick LinksEntrez ID:9318; OMIM: 604508; Uniprot ID:CSN2_HUMAN; ENSEMBL ID: ENSG00000166200; HGNC ID: 30747
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm9535219
GO:0005829TAS-cytosol-
GO:0008180IDA-COP9 signalosome9535219
GO ID Evidence Qualifier GO_term References
GO:0003714IBA-transcription corepressor activity-
GO:0004871NAS-signal transducer activity9535219
GO:0005515IPI-protein binding17438371
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0000338IDA-protein deneddylation19141280
GO:0000715TAS-nucleotide-excision repair, DNA damage recognition-
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006366TAS-transcription from RNA polymerase II promoter7776974
GO:0007165NAS-signal transduction9535219
GO:0008283IEA-cell proliferation-
GO:0022008IBA-neurogenesis-
GO:0030182IEA-neuron differentiation-
GO:0035914IEA-skeletal muscle cell differentiation-
GO:0043687TAS-post-translational protein modification-
GO:0045892IBA-negative regulation of transcription, DNA-templated-
GO:1903507ISS-negative regulation of nucleic acid-templated transcription-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
COPS2NR0B110669510713076 Reconstituted Complex; Two-hybrid
COPS2NR0B111472910713076 Reconstituted Complex; Two-hybrid
COPS2DDB111472916949367 16964240 Affinity Capture-MS
COPS2DDB110800916949367 16964240 Affinity Capture-MS
COPS2IRF811472910991940 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
COPS2IRF810962110991940 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
COPS2ING110983317929852 Affinity Capture-Western; Reconstituted Complex
COPS2ING111472917929852 Affinity Capture-Western; Reconstituted Complex
COPS2ING210983417929852 Affinity Capture-Western; Reconstituted Complex
COPS2ING211472917929852 Affinity Capture-Western; Reconstituted Complex
COPS2NR2F111288310207062 Reconstituted Complex
COPS2NR2F111472910207062 Reconstituted Complex
COPS2THRA11472910207062 10877839 Reconstituted Complex; Two-hybrid
COPS2THRA11292310207062 10877839 Reconstituted Complex; Two-hybrid
COPS2THRB11472910207062 Two-hybrid
COPS2THRB11292410207062 Two-hybrid
COPS2VDR11472910877839 Reconstituted Complex; Two-hybrid
COPS2VDR11326410877839 Reconstituted Complex; Two-hybrid
COPS2CUL4A11402916964240 Affinity Capture-MS
COPS2CUL4A11472916964240 Affinity Capture-MS
COPS2CUL211403111967155 Affinity Capture-Western
COPS2CUL211472911967155 Affinity Capture-Western
COPS2CUL111403211967155 16036220 Affinity Capture-Western
COPS2CUL111472911967155 16036220 Affinity Capture-Western
COPS2COPS311410311967155 16036220 Affinity Capture-MS; Affinity Capture-Western
COPS2COPS311472911967155 16036220 Affinity Capture-MS; Affinity Capture-Western
COPS8COPS21161249707402 11967155 Affinity Capture-Western; Co-purification
COPS8COPS21147299707402 11967155 Affinity Capture-Western; Co-purification
SIN3ACOPS211743910207062 15173382 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIN3ACOPS211472910207062 15173382 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1COPS211497310877839 Reconstituted Complex
NCOR1COPS211472910877839 Reconstituted Complex
RFWD2COPS211472912466024 Co-fractionation
RFWD2COPS212213612466024 Co-fractionation
NIF3L1COPS212192212522100 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NIF3L1COPS211472912522100 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIN3BCOPS211690115173382 Reconstituted Complex
SIN3BCOPS211472915173382 Reconstituted Complex
WDR8COPS211472917353931 Affinity Capture-MS
WDR8COPS211906817353931 Affinity Capture-MS
CPSF1COPS211472918173839 Affinity Capture-Western
CPSF1COPS211894618173839 Affinity Capture-Western
COPS6COPS211617619615732 Affinity Capture-MS
COPS6COPS211472919615732 Affinity Capture-MS
COPS5COPS211618319615732 Affinity Capture-MS
COPS5COPS211472919615732 Affinity Capture-MS
UIMC1COPS211472919615732 Affinity Capture-MS
UIMC1COPS211969719615732 Affinity Capture-MS
KLHL13COPS211472919615732 Affinity Capture-MS
KLHL13COPS212468819615732 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
COPS2GPS126343612615944 CSN1 interacts with CSN2.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1330276
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040625-15'