AutismKB 2.0

Annotation Details for CD22


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CD22 ( FLJ22814,MGC130020,SIGLEC-2,SIGLEC2 )
Gene Full Name: CD22 molecule
Band: 19q13.12
Quick LinksEntrez ID:933; OMIM: 107266; Uniprot ID:CD22_HUMAN; ENSEMBL ID: ENSG00000012124; HGNC ID: 1643
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding8627166
GO:0030246IEA-carbohydrate binding-
GO ID Evidence Qualifier GO_term References
GO:0007155IEA-cell adhesion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CD22AP2A110666912646615 Affinity Capture-Western
CD22AP2A110737112646615 Affinity Capture-Western
CD22CD191073689120258 Affinity Capture-Western
CD22CD191073719120258 Affinity Capture-Western
PLCG1CD221113518627166 Affinity Capture-Western
PLCG1CD221073718627166 Affinity Capture-Western
SYKCD221073718627166 Affinity Capture-Western
SYKCD221127178627166 Affinity Capture-Western
PTPN6CD221073718627166 9890995 10228003 11356834 11551923 Affinity Capture-Western; Biochemical Activity
PTPN6CD221117428627166 9890995 10228003 11356834 11551923 Affinity Capture-Western; Biochemical Activity
PTPRCCD2211175210228003 Affinity Capture-Western
PTPRCCD2210737110228003 Affinity Capture-Western
LYNCD2210737110228003 10748054 Affinity Capture-Western; Biochemical Activity
LYNCD2211024510228003 10748054 Affinity Capture-Western; Biochemical Activity
GRB2CD2210737110748054 11551923 Affinity Capture-Western
GRB2CD2210914210748054 11551923 Affinity Capture-Western
INPP5DCD2210984710748054 Affinity Capture-Western
INPP5DCD2210737110748054 Affinity Capture-Western
SHC1CD2210737110748054 Affinity Capture-Western
SHC1CD2211236110748054 Affinity Capture-Western
AP2M1CD2210758712646615 Two-hybrid
AP2M1CD2210737112646615 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88322
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018