AutismKB 2.0

Annotation Details for TAOK2


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Basic Information Top
Gene Symbol:TAOK2 ( KIAA0881,MAP3K17,PSK,PSK1,PSK1-BETA,TAO1,TAO2 )
Gene Full Name: TAO kinase 2
Band: 16p11.2
Quick LinksEntrez ID:9344; OMIM: 613199; Uniprot ID:TAOK2_HUMAN; ENSEMBL ID: ENSG00000149930; HGNC ID: 16835
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005730IDA-nucleolus-
GO:0005829IDA-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0016021IEA-integral component of membrane-
GO:0030425IEA-dendrite-
GO:0030659IEA-cytoplasmic vesicle membrane-
GO:0031410IDA-cytoplasmic vesicle10660600
GO:0043235IDA-receptor complex23382219
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity10660600
GO:0004702IBA-signal transducer, downstream of receptor, with serine/threonine kinase activity-
GO:0005524IEA-ATP binding-
GO:0031434IPI-mitogen-activated protein kinase kinase binding11279118
GO ID Evidence Qualifier GO_term References
GO:0000186IDA-activation of MAPKK activity10660600
GO:0001558NAS-regulation of cell growth10660600
GO:0006612NAS-protein targeting to membrane10660600
GO:0006915NAS-apoptotic process10660600
GO:0006950IDA-response to stress10660600
GO:0006974IDA-cellular response to DNA damage stimulus17396146
GO:0008360IDA-regulation of cell shape10660600
GO:0016477NAS-cell migration10660600
GO:0030036IDA-actin cytoskeleton organization10660600
GO:0031572IMP-G2 DNA damage checkpoint17396146
GO:0032874IMP-positive regulation of stress-activated MAPK cascade17396146
GO:0046330IDA-positive regulation of JNK cascade10660600
GO:0048041IDA-focal adhesion assembly10660600
GO:0051403IDA-stress-activated MAPK cascade11279118
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TAOK2MAP2K311475011279118 Affinity Capture-Western; Biochemical Activity
TAOK2MAP2K311159211279118 Affinity Capture-Western; Biochemical Activity
TAOK2MAP2K611475011279118 Affinity Capture-Western; Biochemical Activity
TAOK2MAP2K611159411279118 Affinity Capture-Western; Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data