AutismKB 2.0

Annotation Details for MYOCD


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Basic Information Top
Gene Symbol:MYOCD ( MYCD )
Gene Full Name: myocardin
Band: 17p12
Quick LinksEntrez ID:93649; OMIM: 606127; Uniprot ID:MYCD_HUMAN; ENSEMBL ID: ENSG00000141052; HGNC ID: 16067
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IEA-nuclear chromatin-
GO:0005634IDA-nucleus14970199
GO ID Evidence Qualifier GO_term References
GO:0000987IEA-core promoter proximal region sequence-specific DNA binding-
GO:0001046IDA-core promoter sequence-specific DNA binding19797053
GO:0001076ISS-transcription factor activity, RNA polymerase II transcription factor binding-
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding22157009
GO:0001105IBA-RNA polymerase II transcription coactivator activity-
GO:0001228IDA-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding19578358
GO:0005515IPI-protein binding12397177
GO:0008134IPI-transcription factor binding16054032
GO:0035035IEA-histone acetyltransferase binding-
GO:0042826IEA-histone deacetylase binding-
GO:0070412IEA-R-SMAD binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0001560IEA-regulation of cell growth by extracellular stimulus-
GO:0001570IEA-vasculogenesis-
GO:0001666IEP-response to hypoxia19098903
GO:0003231IEA-cardiac ventricle development-
GO:0003257IDA-positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation15907818
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0008285IDA-negative regulation of cell proliferation18451334
GO:0010667IEA-negative regulation of cardiac muscle cell apoptotic process-
GO:0010832IEA-negative regulation of myotube differentiation-
GO:0030511IEA-positive regulation of transforming growth factor beta receptor signaling pathway-
GO:0035051NAS-cardiocyte differentiation12640126
GO:0035065ISS-regulation of histone acetylation-
GO:0035886IEA-vascular smooth muscle cell differentiation-
GO:0043388IEA-positive regulation of DNA binding-
GO:0043954IEA-cellular component maintenance-
GO:0045661IEA-regulation of myoblast differentiation-
GO:0045736IDA-negative regulation of cyclin-dependent protein serine/threonine kinase activity18451334
GO:0045893IDA-positive regulation of transcription, DNA-templated19797053
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter14970199
GO:0045987IDA-positive regulation of smooth muscle contraction17215356
GO:0048286IEA-lung alveolus development-
GO:0048565IEA-digestive tract development-
GO:0051091IDA-positive regulation of sequence-specific DNA binding transcription factor activity19098903
GO:0051145IMP-smooth muscle cell differentiation14970199
GO:0051150TAS-regulation of smooth muscle cell differentiation17215356
GO:0051152IDA-positive regulation of smooth muscle cell differentiation18451334
GO:0055007ISS-cardiac muscle cell differentiation-
GO:0055012IEA-ventricular cardiac muscle cell differentiation-
GO:0060065IEA-uterus development-
GO:0060157IEA-urinary bladder development-
GO:0097070IEA-ductus arteriosus closure-
GO:1900222IMP-negative regulation of amyloid-beta clearance19098903
GO:1900239IEA-regulation of phenotypic switching-
GO:1904706IEA-negative regulation of vascular smooth muscle cell proliferation-
GO:1904753IEA-negative regulation of vascular associated smooth muscle cell migration-
GO:2000587IEA-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-
GO:2000721IDA-positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation15907818
GO:2000724ISS-positive regulation of cardiac vascular smooth muscle cell differentiation-
GO:2000727IDA-positive regulation of cardiac muscle cell differentiation18451334
GO:2001015IDA-negative regulation of skeletal muscle cell differentiation18451334
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MYOCDSMAD212504416224064 Reconstituted Complex
MYOCDSMAD211026216224064 Reconstituted Complex
MYOCDSMAD312504416224064 Affinity Capture-Western; Reconstituted Complex
MYOCDSMAD311026316224064 Affinity Capture-Western; Reconstituted Complex
MYOCDMYOD112504417940050 Reconstituted Complex
MYOCDMYOD111073717940050 Reconstituted Complex
MYOCDSMARCA412504419342595 Affinity Capture-Western; Reconstituted Complex
MYOCDSMARCA411248119342595 Affinity Capture-Western; Reconstituted Complex
MYOCDSRF12504415014501 19342595 Affinity Capture-Western
MYOCDSRF11260015014501 19342595 Affinity Capture-Western
MYOCDKDM3A12504417991879 Reconstituted Complex
MYOCDKDM3A12092717991879 Reconstituted Complex
MYOCDMKL112164214970199 Reconstituted Complex
MYOCDMKL112504414970199 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2137495
  • Data Attributes: MGI curated and HomoloGene calculated
No data