AutismKB 2.0

Annotation Details for ZFYVE9


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Basic Information Top
Gene Symbol:ZFYVE9 ( MADHIP,NSP,SARA,SMADIP )
Gene Full Name: zinc finger, FYVE domain containing 9
Band: 1p32.3
Quick LinksEntrez ID:9372; OMIM: 603755; Uniprot ID:ZFYV9_HUMAN; ENSEMBL ID: ENSG00000157077; HGNC ID: 6775
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005769NAS-early endosome12809483
GO:0005829IDA-cytosol-
GO:0031901IDA-early endosome membrane11877415
GO:0031901TAS-early endosome membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0043234IMP-protein complex15231848
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding9865696
GO:0005545IDA-1-phosphatidylinositol binding11877415
GO:0008236NAS-serine-type peptidase activity9582421
GO:0019904IPI-protein domain specific binding15231848
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006508IEA-proteolysis-
GO:0006897NAS-endocytosis12809483
GO:0007179IMP-transforming growth factor beta receptor signaling pathway9865696
GO:0007179NAS-transforming growth factor beta receptor signaling pathway10615055
GO:0007179TAS-transforming growth factor beta receptor signaling pathway-
GO:0007183IDA-SMAD protein complex assembly9865696
GO:0007184IMP-SMAD protein import into nucleus9865696
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZFYVE9SMAD21147739865696 15356634 Affinity Capture-Western; Reconstituted Complex
ZFYVE9SMAD21102629865696 15356634 Affinity Capture-Western; Reconstituted Complex
ZFYVE9SMAD31147739865696 15356634 Affinity Capture-Western; Reconstituted Complex
ZFYVE9SMAD31102639865696 15356634 Affinity Capture-Western; Reconstituted Complex
ZFYVE9PML11477315356634 Affinity Capture-Western
ZFYVE9PML11138415356634 Affinity Capture-Western
ZFYVE9ST711477312809483 Affinity Capture-Western; Two-hybrid
ZFYVE9ST711369512809483 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
ZFYVE9rs10888748, rs2762818, rs3790522, rs649676 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:2652838
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070705-182'