AutismKB 2.0

Annotation Details for NRXN2


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Basic Information Top
Gene Symbol:NRXN2 ( FLJ40892,KIAA0921 )
Gene Full Name: neurexin 2
Band: 11q13.1
Quick LinksEntrez ID:9379; OMIM: 600566; Uniprot ID:NRX2A_HUMAN; ENSEMBL ID: ENSG00000110076; HGNC ID: 8009
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0043234IEA-protein complex-
GO:0098793IEA-presynapse-
GO ID Evidence Qualifier GO_term References
GO:0004888ISS-transmembrane signaling receptor activity-
GO:0005246ISS-calcium channel regulator activity-
GO:0046872IEA-metal ion binding-
GO:0050839ISS-cell adhesion molecule binding-
GO:0097109ISS-neuroligin family protein binding-
GO ID Evidence Qualifier GO_term References
GO:0007158TAS-neuron cell-cell adhesion18923512
GO:0007165ISS-signal transduction-
GO:0007268ISS-chemical synaptic transmission-
GO:0007269ISS-neurotransmitter secretion-
GO:0007416ISS-synapse assembly-
GO:0030534IMP-adult behavior21424692
GO:0035176IMP-social behavior21424692
GO:0042297IMP-vocal learning21424692
GO:0065009IEA-regulation of molecular function-
GO:0071625IMP-vocalization behavior21424692
GO:0097104ISS-postsynaptic membrane assembly-
GO:0097116ISS-gephyrin clustering involved in postsynaptic density assembly-
GO:0097118ISS-neuroligin clustering involved in postsynaptic membrane assembly-
GO:0097119ISS-postsynaptic density protein 95 clustering-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NRXN2MLLT41104479707552 Two-hybrid
NRXN2MLLT41147809707552 Two-hybrid
NLGN1NRXN21165388576240 Reconstituted Complex
NLGN1NRXN21147808576240 Reconstituted Complex
NLGN2NRXN21216118576240 Reconstituted Complex
NLGN2NRXN21147808576240 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1096362
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070206-5'