AutismKB 2.0

Annotation Details for FOXP2


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Basic Information Top
Gene Symbol:FOXP2 ( CAGH44,DKFZp686H1726,SPCH1,TNRC10 )
Gene Full Name: forkhead box P2
Band: 7q31.1
Quick LinksEntrez ID:93986; OMIM: 605317; Uniprot ID:FOXP2_HUMAN; ENSEMBL ID: ENSG00000128573; HGNC ID: 13875
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000981IBA-RNA polymerase II transcription factor activity, sequence-specific DNA binding-
GO:0001078IEA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003677IDA-DNA binding16407075
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding18987363
GO:0005515IPI-protein binding25027557
GO:0042803IDA-protein homodimerization activity16407075
GO:0043565IDA-sequence-specific DNA binding18987363
GO:0046872IEA-metal ion binding-
GO:0046982IEA-protein heterodimerization activity-
GO:0050681IEA-androgen receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0002053IEA-positive regulation of mesenchymal cell proliferation-
GO:0006351IEA-transcription, DNA-templated-
GO:0007519IEA-skeletal muscle tissue development-
GO:0009791IEA-post-embryonic development-
GO:0021549IEA-cerebellum development-
GO:0021757IMP-caudate nucleus development11872605
GO:0021758IMP-putamen development11872605
GO:0021987IEP-cerebral cortex development18987363
GO:0033574IEA-response to testosterone-
GO:0040007IEA-growth-
GO:0042297IEA-vocal learning-
GO:0043010IEA-camera-type eye development-
GO:0045892IDA-negative regulation of transcription, DNA-templated18987363
GO:0048286IEA-lung alveolus development-
GO:0048745IEA-smooth muscle tissue development-
GO:0060013IEA-righting reflex-
GO:0060501IEA-positive regulation of epithelial cell proliferation involved in lung morphogenesis-
GO:0098582IEA-innate vocalization behavior-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FOXP2CTBP112507314701752 Affinity Capture-Western; Two-hybrid
FOXP2CTBP110786914701752 Affinity Capture-Western; Two-hybrid
FOXP2FOXP111798914701752 Affinity Capture-Western
FOXP2FOXP112507314701752 Affinity Capture-Western
FOXP2GATAD2B12507320185820 Affinity Capture-Western
FOXP2GATAD2B12152920185820 Affinity Capture-Western
FOXP4FOXP212507314701752 Affinity Capture-Western
FOXP4FOXP212547414701752 Affinity Capture-Western
FOXP2FOXP212507314701752 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
FOXP2rs10255943, rs10447760, rs10486026, rs10500038, rs11771168, rs12670585, rs1358278, rs1456021, rs1456029, rs1456031, rs1597548, rs1668335, rs17137124, rs1852469, rs1916977, rs2253478, rs2396722, rs2396753, rs2396765, rs2694941, rs4730626, rs6961558, rs7799652, rs7803667, rs923875 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:2148705
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041203-2'