AutismKB 2.0

Annotation Details for SYTL4


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Basic Information Top
Gene Symbol:SYTL4 ( DKFZp451P0116,FLJ40960,SLP4 )
Gene Full Name: synaptotagmin-like 4
Band: Xq22.1
Quick LinksEntrez ID:94121; OMIM: 300723; Uniprot ID:SYTL4_HUMAN; ENSEMBL ID: ENSG00000102362; HGNC ID: 15588
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005768IDA-endosome19966785
GO:0005815IDA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005886IBA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0019898ISS-extrinsic component of membrane-
GO:0030658IEA-transport vesicle membrane-
GO:0031092TAS-platelet alpha granule membrane-
GO:0070382IBA-exocytic vesicle-
GO:0098793IEA-presynapse-
GO ID Evidence Qualifier GO_term References
GO:0005509IBA-calcium ion binding-
GO:0005515IPI-protein binding25416956
GO:0005543ISS-phospholipid binding-
GO:0005544IBA-calcium-dependent phospholipid binding-
GO:0017137IEA-Rab GTPase binding-
GO:0019905IBA-syntaxin binding-
GO:0030276IBA-clathrin binding-
GO:0042043ISS-neurexin family protein binding-
GO ID Evidence Qualifier GO_term References
GO:0002576TAS-platelet degranulation-
GO:0006886IEA-intracellular protein transport-
GO:0006906IBA-vesicle fusion-
GO:0017158IBA-regulation of calcium ion-dependent exocytosis-
GO:0045921IMP-positive regulation of exocytosis19966785
GO:0046676IEA-negative regulation of insulin secretion-
GO:0048791IBA-calcium ion-regulated exocytosis of neurotransmitter-
GO:0050714IMP-positive regulation of protein secretion19966785
GO:0071985IMP-multivesicular body sorting pathway19966785
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SYTL4RAB8A11038211773082 12176990 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL4RAB8A12512011773082 12176990 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL4RAB3A12512011773082 11865063 12590134 Affinity Capture-Western; Two-hybrid
SYTL4RAB3A11180211773082 11865063 12590134 Affinity Capture-Western; Two-hybrid
SYTL4RAB27A12512011773082 11865063 12101244 12176990 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL4RAB27A11181111773082 11865063 12101244 12176990 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL4RAB27B12512011956164 Affinity Capture-Western; Reconstituted Complex
SYTL4RAB27B11181211956164 Affinity Capture-Western; Reconstituted Complex
SYTL4STX1A12512012101244 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL4STX1A11267612101244 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL4STXBP112512012590134 Affinity Capture-Western
SYTL4STXBP111268112590134 Affinity Capture-Western
SYTL4USP2011607719615732 Affinity Capture-MS
SYTL4USP2012512019615732 Affinity Capture-MS
SYTL4CCDC85B12512016189514 Two-hybrid
SYTL4CCDC85B11619816189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1351606
  • Data Attributes: MGI curated and HomoloGene calculated
No data