AutismKB 2.0

Annotation Details for TJP2


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Basic Information Top
Gene Symbol:TJP2 ( MGC26306,X104,ZO2 )
Gene Full Name: tight junction protein 2 (zona occludens 2)
Band: 9q21.11
Quick LinksEntrez ID:9414; OMIM: 607709; Uniprot ID:ZO2_HUMAN; ENSEMBL ID: ENSG00000119139; HGNC ID: 11828
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005912IEA-adherens junction-
GO:0005923IDA-bicellular tight junction22006950
GO:0030054IDA-cell junction-
GO ID Evidence Qualifier GO_term References
GO:0004385TAS-guanylate kinase activity8824195
GO:0005515IPI-protein binding15975580
GO:0008022IEA-protein C-terminus binding-
GO:0019904IPI-protein domain specific binding23885123
GO:0030674IDA-protein binding, bridging23885123
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0035329TAS-hippo signaling-
GO:0046037IEA-GMP metabolic process-
GO:0046710IEA-GDP metabolic process-
GO:0050892IMP-intestinal absorption23885123
GO:0071847IEA-TNFSF11-mediated signaling pathway-
GO:0090557IMP-establishment of endothelial intestinal barrier23885123
GO:0090559IMP-regulation of membrane permeability23885123
GO:2001205IEA-negative regulation of osteoclast development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TJP2CTNNA111480910026224 Reconstituted Complex
TJP2CTNNA110787610026224 Reconstituted Complex
TJP2EPB4110834910874042 Affinity Capture-Western; Two-hybrid
TJP2EPB4111480910874042 Affinity Capture-Western; Two-hybrid
TJP2SFN11480915778465 Affinity Capture-MS
TJP2SFN10907215778465 Affinity Capture-MS
TJP2TJP11148099792688 10026224 10575001 Affinity Capture-Western; Reconstituted Complex
TJP2TJP11129379792688 10026224 10575001 Affinity Capture-Western; Reconstituted Complex
TJP2TRAF611480917353931 Affinity Capture-MS
TJP2TRAF611304117353931 Affinity Capture-MS
TJP2YWHAB11336117353931 Affinity Capture-MS
TJP2YWHAB11480917353931 Affinity Capture-MS
TJP2YWHAG11480917353931 Affinity Capture-MS
TJP2YWHAG11336417353931 Affinity Capture-MS
TJP2YWHAZ11480917353931 Affinity Capture-MS
TJP2YWHAZ11336617353931 Affinity Capture-MS
TJP2RAE111480919615732 Affinity Capture-MS
TJP2RAE111405419615732 Affinity Capture-MS
TJP2CLDN111480910601346 Reconstituted Complex
TJP2CLDN111453310601346 Reconstituted Complex
TJP2HGS11480919019082 Reconstituted Complex
TJP2HGS11459319019082 Reconstituted Complex
LOC100506658TJP211480910026224 10575001 14512431 Affinity Capture-Western; Reconstituted Complex
LOC100506658TJP211100410026224 10575001 14512431 Affinity Capture-Western; Reconstituted Complex
CGNTJP211480911042084 Reconstituted Complex
CGNTJP212158911042084 Reconstituted Complex
SH3KBP1TJP211902912829691 Affinity Capture-Western
SH3KBP1TJP211480912829691 Affinity Capture-Western
SRRM2TJP211480916159877 Affinity Capture-MS
SRRM2TJP211707116159877 Affinity Capture-MS
YWHAQTJP211616817353931 Affinity Capture-MS
YWHAQTJP211480917353931 Affinity Capture-MS
KBTBD7TJP211480920562859 Affinity Capture-MS
KBTBD7TJP212387320562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1341872
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-58'