AutismKB 2.0

Annotation Details for TNFSF8


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Basic Information Top
Gene Symbol:TNFSF8 ( CD153,CD30L,CD30LG,MGC138144 )
Gene Full Name: tumor necrosis factor (ligand) superfamily, member 8
Band: 9q32-q33.1
Quick LinksEntrez ID:944; OMIM: 603875; Uniprot ID:TNFL8_HUMAN; ENSEMBL ID: ENSG00000106952; HGNC ID: 11938
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IEA-extracellular space-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane8391931
GO ID Evidence Qualifier GO_term References
GO:0005102TAS-receptor binding8391931
GO:0005125IEA-cytokine activity-
GO:0005164IEA-tumor necrosis factor receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0006915TAS-apoptotic process8391931
GO:0006955IEA-immune response-
GO:0007165TAS-signal transduction8391931
GO:0007267TAS-cell-cell signaling8391931
GO:0008283TAS-cell proliferation8391931
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0043374IEA-CD8-positive, alpha-beta T cell differentiation-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0050830IEA-defense response to Gram-positive bacterium-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNFSF8TNFRSF810738111754357 Reconstituted Complex
TNFSF8TNFRSF810738211754357 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88328
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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