Annotation Details for AIM2
Basic Information Top
| Gene Symbol: | AIM2 ( PYHIN4 ) |
|---|---|
| Gene Full Name: | absent in melanoma 2 |
| Band: | 1q23.1-q23.2 |
| Quick Links | Entrez ID:9447; OMIM: 604578; Uniprot ID:AIM2_HUMAN; ENSEMBL ID: ENSG00000163568; HGNC ID: 357 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005654 | IDA | - | nucleoplasm | - |
| GO:0005737 | IDA | - | cytoplasm | 19158676 |
| GO:0005739 | IDA | - | mitochondrion | - |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0097169 | IDA | - | AIM2 inflammasome complex | 19158676 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003690 | IDA | - | double-stranded DNA binding | 19158675 |
| GO:0005515 | IPI | - | protein binding | 19158676 |
| GO:0042802 | IPI | - | identical protein binding | 19158676 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0002218 | IDA | - | activation of innate immune response | 19158675 |
| GO:0002230 | ISS | - | positive regulation of defense response to virus by host | - |
| GO:0006915 | IEA | - | apoptotic process | - |
| GO:0006954 | IEA | - | inflammatory response | - |
| GO:0006955 | TAS | - | immune response | 9242382 |
| GO:0032088 | IDA | - | negative regulation of NF-kappaB transcription factor activity | 16432157 |
| GO:0032461 | IDA | - | positive regulation of protein oligomerization | 19158676 |
| GO:0032731 | IDA | - | positive regulation of interleukin-1 beta production | 19158675 |
| GO:0033209 | IDA | - | tumor necrosis factor-mediated signaling pathway | 16432157 |
| GO:0035458 | IEA | - | cellular response to interferon-beta | - |
| GO:0035690 | IDA | - | cellular response to drug | 19158679 |
| GO:0045087 | IEA | - | innate immune response | - |
| GO:0050702 | IMP | - | interleukin-1 beta secretion | 19158679 |
| GO:0050718 | IDA | - | positive regulation of interleukin-1 beta secretion | 19158679 |
| GO:0051092 | IDA | - | positive regulation of NF-kappaB transcription factor activity | 19158675 |
| GO:0070269 | IDA | - | pyroptosis | 19158675 |
| GO:2001056 | IDA | - | positive regulation of cysteine-type endopeptidase activity | 19158676 |
Protein-Protein Interaction