AutismKB 2.0

Annotation Details for IL27RA


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Basic Information Top
Gene Symbol:IL27RA ( CRL1,IL27R,TCCR,WSX1,zcytor1 )
Gene Full Name: interleukin 27 receptor, alpha
Band: 19p13.12
Quick LinksEntrez ID:9466; OMIM: 605350; Uniprot ID:I27RA_HUMAN; ENSEMBL ID: ENSG00000104998; HGNC ID: 17290
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane9600072
GO ID Evidence Qualifier GO_term References
GO:0004888TAS-transmembrane signaling receptor activity9600072
GO:0045509IEA-interleukin-27 receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0002827IEA-positive regulation of T-helper 1 type immune response-
GO:0002829IEA-negative regulation of type 2 immune response-
GO:0006955TAS-immune response9600072
GO:0007166TAS-cell surface receptor signaling pathway9600072
GO:0032729IEA-positive regulation of interferon-gamma production-
GO:0048302IEA-regulation of isotype switching to IgG isotypes-
GO:0050830IEA-defense response to Gram-positive bacterium-
GO:0070106IEA-interleukin-27-mediated signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IL27RAJAK110991912734330 Affinity Capture-Western
IL27RAJAK111485212734330 Affinity Capture-Western
IL27RASTAT111264912734330 Affinity Capture-Western; Reconstituted Complex
IL27RASTAT111485212734330 Affinity Capture-Western; Reconstituted Complex
EBI3IL27RA11545012121660 Affinity Capture-Western
EBI3IL27RA11485212121660 Affinity Capture-Western
GOSR1IL27RA11490312121660 Affinity Capture-Western
GOSR1IL27RA11485212121660 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1355318
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018