AutismKB 2.0

Annotation Details for CD34


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CD34 ( - )
Gene Full Name: CD34 molecule
Band: 1q32.2
Quick LinksEntrez ID:947; OMIM: 142230; Uniprot ID:CD34_HUMAN; ENSEMBL ID: ENSG00000174059; HGNC ID: 1662
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm7525669
GO:0005764ISS-lysosome-
GO:0005886IDA-plasma membrane1868864
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane9042286
GO:0009897IC-external side of plasma membrane15249540
GO:0009897IDA-external side of plasma membrane10337918
GO:0009925ISS-basal plasma membrane-
GO:0016324ISS-apical plasma membrane-
GO:0036053ISS-glomerular endothelium fenestra-
GO:0045171IDA-intercellular bridge7525669
GO:0048471IDA-perinuclear region of cytoplasm7525669
GO ID Evidence Qualifier GO_term References
GO:0008134IPI-transcription factor binding21873977
GO:0030246IDA-carbohydrate binding15249540
GO:0043199IEA-sulfate binding-
GO ID Evidence Qualifier GO_term References
GO:0001894IDA-tissue homeostasis12939361
GO:0001935IDA-endothelial cell proliferation21835908
GO:0003094IEP-glomerular filtration20354148
GO:0003158IEP-endothelium development17261663
GO:0007160IBA-cell-matrix adhesion-
GO:0007165IEP-signal transduction17261663
GO:0008217IDA-regulation of blood pressure17505307
GO:0008283ISS-cell proliferation-
GO:0010628IEP-positive regulation of gene expression17261663
GO:0010629IMP-negative regulation of gene expression15969628
GO:0016337IDA-single organismal cell-cell adhesion15249540
GO:0030097IMP-hemopoiesis15969628
GO:0030195IDA-negative regulation of blood coagulation17505307
GO:0032720IDA-negative regulation of tumor necrosis factor production17505307
GO:0032733IDA-positive regulation of interleukin-10 production17505307
GO:0035759ISS-mesangial cell-matrix adhesion-
GO:0038001IDA-paracrine signaling21835908
GO:0042482IDA-positive regulation of odontogenesis12939361
GO:0045019IDA-negative regulation of nitric oxide biosynthetic process17505307
GO:0045766IDA-positive regulation of angiogenesis12939361
GO:0048870IEP-cell motility17261663
GO:0050776TAS-regulation of immune response-
GO:0050900ISS-leukocyte migration-
GO:0060290IEP-transdifferentiation1868864
GO:0061042IEP-vascular wound healing20354148
GO:0071425IMP-hematopoietic stem cell proliferation21873977
GO:0071636IDA-positive regulation of transforming growth factor beta production17505307
GO:0071657IDA-positive regulation of granulocyte colony-stimulating factor production9815891
GO:0071657IEP-positive regulation of granulocyte colony-stimulating factor production17261663
GO:0071971IDA-extracellular exosome assembly21835908
GO:0072011IEP-glomerular endothelium development17464107
GO:0072089IEP-stem cell proliferation17261663
GO:0072254IEP-metanephric glomerular mesangial cell differentiation1868864
GO:1900035IDA-negative regulation of cellular response to heat17505307
GO:1900038IDA-negative regulation of cellular response to hypoxia17505307
GO:1900041IMP-negative regulation of interleukin-2 secretion9815891
GO:1900168IDA-positive regulation of glial cell-derived neurotrophic factor secretion17505307
GO:1901215IDA-negative regulation of neuron death17505307
GO:2001214IDA-positive regulation of vasculogenesis12939361
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CREMCD3410778010373550 Two-hybrid
CREMCD3410738510373550 Two-hybrid
ATF5CD3411648710373550 Two-hybrid
ATF5CD3410738510373550 Two-hybrid
CRKLCD3410778911389015 Affinity Capture-Western; Reconstituted Complex
CRKLCD3410738511389015 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88329
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved