AutismKB 2.0

Annotation Details for MAPK8IP1


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Basic Information Top
Gene Symbol:MAPK8IP1 ( IB1,JIP-1,JIP1,PRKM8IP )
Gene Full Name: mitogen-activated protein kinase 8 interacting protein 1
Band: 11p11.2
Quick LinksEntrez ID:9479; OMIM: 604641; Uniprot ID:JIP1_HUMAN; ENSEMBL ID: ENSG00000121653; HGNC ID: 6882
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005737IDA-cytoplasm10574993
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0005829IEA-cytosol-
GO:0031966IEA-mitochondrial membrane-
GO:0044294IEA-dendritic growth cone-
GO:0044295IEA-axonal growth cone-
GO:0044297IEA-cell body-
GO:0044302IEA-dentate gyrus mossy fiber-
GO:0045202IEA-synapse-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0004860TAS-protein kinase inhibitor activity9933567
GO:0005078IPI-MAP-kinase scaffold activity11238452
GO:0005515IPI-protein binding11517249
GO:0008432IEA-JUN kinase binding-
GO:0019894IPI-kinesin binding11238452
GO:0031434IEA-mitogen-activated protein kinase kinase binding-
GO:0031435IEA-mitogen-activated protein kinase kinase kinase binding-
GO ID Evidence Qualifier GO_term References
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0007258IEA-JUN phosphorylation-
GO:0009967IEA-positive regulation of signal transduction-
GO:0016192ISS-vesicle-mediated transport-
GO:0043508IEA-negative regulation of JUN kinase activity-
GO:0046328ISS-regulation of JNK cascade-
GO:2001243IEA-negative regulation of intrinsic apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAPK8IP1AKT111486412194869 Affinity Capture-Western
MAPK8IP1AKT110671012194869 Affinity Capture-Western
MAPK8IP1LRP111486410827173 Reconstituted Complex; Two-hybrid
MAPK8IP1LRP111021510827173 Reconstituted Complex; Two-hybrid
MAPK8IP1LRP211021610827173 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP1LRP211486410827173 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP1MAP3K1011044010490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAP3K1011486410490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAP3K1111486410490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAP3K1111044210490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1PAX211111011700324 Affinity Capture-Western
MAPK8IP1PAX211486411700324 Affinity Capture-Western
MAPK8IP1MAPK81148649733513 11700324 Affinity Capture-Western
MAPK8IP1MAPK81115859733513 11700324 Affinity Capture-Western
MAPK8IP1MAPK91148649733513 10490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAPK91115879733513 10490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAP2K711486410490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAP2K711159510490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1TIAM111486412024021 Affinity Capture-Western
MAPK8IP1TIAM111293012024021 Affinity Capture-Western
MAPK8IP1MAP3K1211356610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1MAP3K1211486410490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP1LRP811486410827173 Two-hybrid
MAPK8IP1LRP811357910827173 Two-hybrid
MAPK8IP1MAP3K1311461411726277 Affinity Capture-Western
MAPK8IP1MAP3K1311486411726277 Affinity Capture-Western
MAPK8IP1RECQL511486416169070 Two-hybrid
MAPK8IP1RECQL511479716169070 Two-hybrid
MAPK8IP1MAPK8IP111486410490659 Affinity Capture-Western
MAPK8IP2MAPK8IP111486410490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAPK8IP111708610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP3MAPK8IP111486410629060 Reconstituted Complex
MAPK8IP3MAPK8IP111677410629060 Reconstituted Complex
DUSP16MAPK8IP111486412524447 Affinity Capture-Western; Reconstituted Complex
DUSP16MAPK8IP112332112524447 Affinity Capture-Western; Reconstituted Complex
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AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
MAPK8IP1rs1554338 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:1309464
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-101025-1'