AutismKB 2.0

Annotation Details for SCARB1


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Basic Information Top
Gene Symbol:SCARB1 ( CD36L1,CLA-1,CLA1,MGC138242,SR-BI,SRB1 )
Gene Full Name: scavenger receptor class B, member 1
Band: 12q24.31
Quick LinksEntrez ID:949; OMIM: 601040; Uniprot ID:SCRB1_HUMAN; ENSEMBL ID: ENSG00000073060; HGNC ID: 1664
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005765IDA-lysosomal membrane17897319
GO:0005886IDA-plasma membrane9211901
GO:0005886TAS-plasma membrane-
GO:0005887IEA-integral component of plasma membrane-
GO:0005901TAS-caveola12651854
GO:0009986ISS-cell surface21481393
GO:0030666TAS-endocytic vesicle membrane-
GO:0031528IEA-microvillus membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0001530IDA-lipopolysaccharide binding12651854
GO:0001618IEA-virus receptor activity-
GO:0001786ISS-phosphatidylserine binding-
GO:0001875IDA-lipopolysaccharide receptor activity12651854
GO:0005215TAS-transporter activity9211901
GO:0005515IPI-protein binding12356718
GO:0005545TAS-1-phosphatidylinositol binding9211901
GO:0008035IEA-high-density lipoprotein particle binding-
GO:0030169IDA-low-density lipoprotein particle binding9211901
GO:0034185IPI-apolipoprotein binding10764676
GO:0034186IPI-apolipoprotein A-I binding10764676
GO:0042803IEA-protein homodimerization activity-
GO:0070506IDA-high-density lipoprotein particle receptor activity9211901
GO:0070506IMP-high-density lipoprotein particle receptor activity11208913
GO ID Evidence Qualifier GO_term References
GO:0001935IEA-endothelial cell proliferation-
GO:0006702IEA-androgen biosynthetic process-
GO:0006707IEA-cholesterol catabolic process-
GO:0006898TAS-receptor-mediated endocytosis-
GO:0010595TAS-positive regulation of endothelial cell migration17574123
GO:0010867ISS-positive regulation of triglyceride biosynthetic process-
GO:0010886IDA-positive regulation of cholesterol storage9211901
GO:0010899ISS-regulation of phosphatidylcholine catabolic process-
GO:0015914ISS-phospholipid transport-
GO:0015920IDA-lipopolysaccharide transport12651854
GO:0031663IEA-lipopolysaccharide-mediated signaling pathway-
GO:0032497IDA-detection of lipopolysaccharide12651854
GO:0033344IMP-cholesterol efflux12202492
GO:0033344ISS-cholesterol efflux14718538
GO:0034375ISS-high-density lipoprotein particle remodeling-
GO:0034383ISS-low-density lipoprotein particle clearance-
GO:0034384IDA-high-density lipoprotein particle clearance9211901
GO:0034384TAS-high-density lipoprotein particle clearance-
GO:0035461IMP-vitamin transmembrane transport11208913
GO:0042060TAS-wound healing17574123
GO:0042632ISS-cholesterol homeostasis-
GO:0043534IEA-blood vessel endothelial cell migration-
GO:0043654IDA-recognition of apoptotic cell9211901
GO:0043691IEP-reverse cholesterol transport9211901
GO:0044406IMP-adhesion of symbiont to host19087225
GO:0046718IEA-viral entry into host cell-
GO:0050764IC-regulation of phagocytosis9211901
GO:0050892IEA-intestinal absorption-
GO:0051000IDA-positive regulation of nitric-oxide synthase activity11792700
GO:0070328ISS-triglyceride homeostasis-
GO:0070508IMP-cholesterol import11208913
GO:0070508ISS-cholesterol import14718538
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDZK1SCARB111120012119305 Affinity Capture-Western
PDZK1SCARB110738712119305 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
SCARB1rs4238001 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:893578
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031126-1'