AutismKB 2.0

Annotation Details for GABBR2


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Basic Information Top
Gene Symbol:GABBR2 ( FLJ36928,GABABR2,GPR51,GPRC3B,HG20,HRIHFB2099 )
Gene Full Name: gamma-aminobutyric acid (GABA) B receptor, 2
Band: 9q22.33
Quick LinksEntrez ID:9568; OMIM: 607340; Uniprot ID:GABR2_HUMAN; ENSEMBL ID: ENSG00000136928; HGNC ID: 4507
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane9872316
GO:0030054IEA-cell junction-
GO:0038039IPI-G-protein coupled receptor heterodimeric complex9872316
GO:0043005IEA-neuron projection-
GO:0045211IEA-postsynaptic membrane-
GO:1902710IDA-GABA receptor complex15304491
GO ID Evidence Qualifier GO_term References
GO:0004965IDAcontributes_toG-protein coupled GABA receptor activity9872316
GO:0005515IPI-protein binding16724110
GO:0046982IPI-protein heterodimerization activity15304491
GO ID Evidence Qualifier GO_term References
GO:0007186TAS-G-protein coupled receptor signaling pathway9872316
GO:0007194TAS-negative regulation of adenylate cyclase activity10328880
GO:0007214IDA-gamma-aminobutyric acid signaling pathway9872316
GO:0007268TAS-chemical synaptic transmission9872316
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GABBR2ATF410695811087824 Affinity Capture-Western
GABBR2ATF411493811087824 Affinity Capture-Western
GABBR2GABBR11088259872316 Affinity Capture-Western; Two-hybrid
GABBR2GABBR11149389872316 Affinity Capture-Western; Two-hybrid
GABBR2SH3GL311235416169070 Two-hybrid
GABBR2SH3GL311493816169070 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
GABBR2GABBR121428815660124 GB1 interacts with GB2.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2386030
  • Data Attributes: MGI curated and HomoloGene calculated
No data