AutismKB 2.0

Annotation Details for NCOR1


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Basic Information Top
Gene Symbol:NCOR1 ( KIAA1047,MGC104216,N-CoR,N-CoR1,TRAC1,hN-CoR )
Gene Full Name: nuclear receptor corepressor 1
Band: 17p12-p11.2
Quick LinksEntrez ID:9611; OMIM: 600849; Uniprot ID:NCOR1_HUMAN; ENSEMBL ID: ENSG00000141027; HGNC ID: 7672
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000118IDAcolocalizes_withhistone deacetylase complex18326024
GO:0000790IDA-nuclear chromatin17505061
GO:0005634IC-nucleus18052923
GO:0005634IDA-nucleus10049357
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005876IDA-spindle microtubule18326024
GO:0016020IDA-membrane19946888
GO:0016580IDAcolocalizes_withSin3 complex11486045
GO:0017053IDA-transcriptional repressor complex11804585
GO ID Evidence Qualifier GO_term References
GO:0001102IPI-RNA polymerase II activating transcription factor binding19955185
GO:0003714IDA-transcription corepressor activity18052923
GO:0003714IMP-transcription corepressor activity12628926
GO:0005515IPI-protein binding10049357
GO:0016922IBA-ligand-dependent nuclear receptor binding-
GO:0035257IPI-nuclear hormone receptor binding9328355
GO:0042826IPI-histone deacetylase binding11804585
GO:0044212ISS-transcription regulatory region DNA binding-
GO:0046966IBA-thyroid hormone receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter12628926
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter-
GO:0006366TAS-transcription from RNA polymerase II promoter7566114
GO:0007623TAS-circadian rhythm-
GO:0016569IEA-covalent chromatin modification-
GO:0019216TAS-regulation of lipid metabolic process-
GO:0046329IDA-negative regulation of JNK cascade11931768
GO:0051225IMP-spindle assembly18326024
GO:0072362IMP-regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter19955185
GO:0072368IMP-regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter19955185
GO:1903799IMP-negative regulation of production of miRNAs involved in gene silencing by miRNA20388878
GO:2000191IC-regulation of fatty acid transport19955185
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NCOR1AR11497311971970 12089345 14593076 15256534 15598662 16914745 Affinity Capture-Western; Co-localization; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
NCOR1AR10686211971970 12089345 14593076 15256534 15598662 16914745 Affinity Capture-Western; Co-localization; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
NCOR1BACH111497319011633 Affinity Capture-Western
NCOR1BACH110704719011633 Affinity Capture-Western
NCOR1BCL610707610898795 11865059 15454082 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1BCL611497310898795 11865059 15454082 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1RUNX111497310882117 Reconstituted Complex
NCOR1RUNX110730910882117 Reconstituted Complex
NCOR1RUNX1T11149739819405 10882117 11113190 11533236 15333839 16227606 Affinity Capture-Western; Reconstituted Complex
NCOR1RUNX1T11073109819405 10882117 11113190 11533236 15333839 16227606 Affinity Capture-Western; Reconstituted Complex
NCOR1CBFA2T311497311533236 18586123 Affinity Capture-Western
NCOR1CBFA2T310731111533236 18586123 Affinity Capture-Western
NCOR1CEBPB11497315870285 Affinity Capture-Western
NCOR1CEBPB10748015870285 Affinity Capture-Western
NCOR1CHD110753012890497 Affinity Capture-Western; Two-hybrid
NCOR1CHD111497312890497 Affinity Capture-Western; Two-hybrid
NCOR1CLK110760612890497 Two-hybrid
NCOR1CLK111497312890497 Two-hybrid
NCOR1CREBBP11497317073437 Affinity Capture-Western; Co-fractionation; Co-purification
NCOR1CREBBP10777717073437 Affinity Capture-Western; Co-fractionation; Co-purification
NCOR1DACH111497317182846 Affinity Capture-Western
NCOR1DACH110797217182846 Affinity Capture-Western
NCOR1EMD11497317620012 Affinity Capture-Western
NCOR1EMD10832517620012 Affinity Capture-Western
NCOR1EP30010834717073437 Affinity Capture-Western
NCOR1EP30011497317073437 Affinity Capture-Western
NCOR1ESR110840312145334 17400812 Affinity Capture-Western; Reconstituted Complex
NCOR1ESR111497312145334 17400812 Affinity Capture-Western; Reconstituted Complex
NCOR1ETS111497315788656 Affinity Capture-Western
NCOR1ETS110841415788656 Affinity Capture-Western
NCOR1ETS211497315788656 Affinity Capture-Western
NCOR1ETS210841515788656 Affinity Capture-Western
NCOR1ETV611497311001911 11439334 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1ETV610842111001911 11439334 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1GPS211497311931768 12628926 14527417 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
NCOR1GPS210913211931768 12628926 14527417 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
NCOR1NR3C110916512011091 12569182 15016838 15870285 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1NR3C111497312011091 12569182 15016838 15870285 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1GTF2B1149739611234 Reconstituted Complex
NCOR1GTF2B1092149611234 Reconstituted Complex
NCOR1HTT11497310441327 Two-hybrid
NCOR1HTT10931410441327 Two-hybrid
NCOR1HSPA411497314527417 Affinity Capture-MS
NCOR1HSPA410954014527417 Affinity Capture-MS
NCOR1KIF1111003014527417 Affinity Capture-MS
NCOR1KIF1111497314527417 Affinity Capture-MS
NCOR1MECP211497311441023 Reconstituted Complex
NCOR1MECP211036811441023 Reconstituted Complex
NCOR1ATXN311497317079677 Affinity Capture-Western; Reconstituted Complex
NCOR1ATXN311043317079677 Affinity Capture-Western; Reconstituted Complex
NCOR1MYB11497314761981 Affinity Capture-Western; Reconstituted Complex
NCOR1MYB11068714761981 Affinity Capture-Western; Reconstituted Complex
NCOR1MYOD111073710406466 Reconstituted Complex
NCOR1MYOD111497310406466 Reconstituted Complex
NCOR1NFE2L211497315870285 Affinity Capture-Western
NCOR1NFE2L211085215870285 Affinity Capture-Western
NCOR1NFKB111085712150997 Affinity Capture-Western
NCOR1NFKB111497312150997 Affinity Capture-Western
NCOR1NFKBIA11085915536134 Affinity Capture-Western
NCOR1NFKBIA11497315536134 Affinity Capture-Western
NCOR1CNOT211497316712523 Two-hybrid
NCOR1CNOT211091016712523 Two-hybrid
NCOR1PDCD211116112149646 Affinity Capture-Western
NCOR1PDCD211497312149646 Affinity Capture-Western
NCOR1PGR11126019147702 Affinity Capture-Western
NCOR1PGR11497319147702 Affinity Capture-Western
NCOR1PHB11126412466959 Affinity Capture-Western
NCOR1PHB11497312466959 Affinity Capture-Western
NCOR1PML11138410882117 11430826 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1PML11497310882117 11430826 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1POU1F11114459751061 16030140 Affinity Capture-Western; Reconstituted Complex
NCOR1POU1F11149739751061 16030140 Affinity Capture-Western; Reconstituted Complex
NCOR1PPARA11497310336495 15870285 18292238 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1PPARA11146110336495 15870285 18292238 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1PPARD11497311867749 Two-hybrid
NCOR1PPARD11146311867749 Two-hybrid
NCOR1PPARG11497315681609 16127449 Co-localization; Two-hybrid
NCOR1PPARG11146415681609 16127449 Co-localization; Two-hybrid
NCOR1PPP1CA11497312410313 Affinity Capture-Western
NCOR1PPP1CA11149312410313 Affinity Capture-Western
NCOR1PPP1CB11149412410313 Affinity Capture-Western
NCOR1PPP1CB11497312410313 Affinity Capture-Western
NCOR1PPP1CC11149512410313 Affinity Capture-Western
NCOR1PPP1CC11497312410313 Affinity Capture-Western
NCOR1PTMA11172412634383 Reconstituted Complex
NCOR1PTMA11497312634383 Reconstituted Complex
NCOR1RARA1149739486655 9531570 10336495 10882117 15336696 18978041 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1RARA1118499486655 9531570 10336495 10882117 15336696 18978041 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1RARG11497310336495 Reconstituted Complex; Two-hybrid
NCOR1RARG11185110336495 Reconstituted Complex; Two-hybrid
NCOR1REST11191017468742 Affinity Capture-MS
NCOR1REST11497317468742 Affinity Capture-MS
NCOR1RXRA11497315116119 Reconstituted Complex
NCOR1RXRA11216815116119 Reconstituted Complex
NCOR1SAFB11220116195251 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1SAFB11497316195251 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1SKI11238811430826 19032343 Affinity Capture-Western; Reconstituted Complex
NCOR1SKI11497311430826 19032343 Affinity Capture-Western; Reconstituted Complex
NCOR1SKIL11238910049357 Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
NCOR1SKIL11497310049357 Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
NCOR1SMARCA411248111013263 Co-purification
NCOR1SMARCA411497311013263 Co-purification
NCOR1SMARCB111497311013263 Co-purification
NCOR1SMARCB111248211013263 Co-purification
NCOR1SMARCC111248311013263 Co-purification
NCOR1SMARCC111497311013263 Co-purification
NCOR1SMARCC211248511013263 Co-purification
NCOR1SMARCC211497311013263 Co-purification
NCOR1SP111255015878880 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1SP111497315878880 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1TAF61149739611234 Reconstituted Complex
NCOR1TAF61127419611234 Reconstituted Complex
NCOR1TAF91127439611234 Reconstituted Complex; Two-hybrid
NCOR1TAF91149739611234 Reconstituted Complex; Two-hybrid
NCOR1TBL1X11497310809664 10944117 11931768 12628926 18202150 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
NCOR1TBL1X11277010809664 10944117 11931768 12628926 18202150 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
NCOR1TCF311279115934135 16252006 Affinity Capture-Western
NCOR1TCF311497315934135 16252006 Affinity Capture-Western
NCOR1THRA1149739804773 9849963 11889044 15131262 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1THRA1129239804773 9849963 11889044 15131262 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1THRB11497314985366 15336696 19211732 Reconstituted Complex; Two-hybrid
NCOR1THRB11292414985366 15336696 19211732 Reconstituted Complex; Two-hybrid
NCOR1TP5311301019011633 Affinity Capture-Western
NCOR1TP5311497319011633 Affinity Capture-Western
NCOR1UBC11316414701861 Affinity Capture-Western
NCOR1UBC11497314701861 Affinity Capture-Western
NCOR1UBE2I11317716421255 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1UBE2I11497316421255 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1NR1H211497312663743 Two-hybrid
NCOR1NR1H211322212663743 Two-hybrid
NCOR1VDR1132649878542 10877839 12460926 16252006 19098224 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1VDR1149739878542 10877839 12460926 16252006 19098224 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1CORO2A11330212628926 14527417 Affinity Capture-MS; Affinity Capture-Western
NCOR1CORO2A11497312628926 14527417 Affinity Capture-MS; Affinity Capture-Western
NCOR1ZBTB161134989531570 11865059 16024608 Affinity Capture-Western; Reconstituted Complex
NCOR1ZBTB161149739531570 11865059 16024608 Affinity Capture-Western; Reconstituted Complex
NCOR1RDBP11366214667819 Two-hybrid
NCOR1RDBP11497314667819 Two-hybrid
NCOR1NCOA311497312089344 Affinity Capture-Western; Reconstituted Complex
NCOR1NCOA311384112089344 Affinity Capture-Western; Reconstituted Complex
NCOR1KDM5C11387017468742 Affinity Capture-MS
NCOR1KDM5C11497317468742 Affinity Capture-MS
NCOR1HIST1H3A11394612840002 Reconstituted Complex
NCOR1HIST1H3A11497312840002 Reconstituted Complex
NCOR1HIST1H4A11497315832170 Reconstituted Complex
NCOR1HIST1H4A11395515832170 Reconstituted Complex
NCOR1PIAS111412416421255 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1PIAS111497316421255 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1NCOA111420012569182 Reconstituted Complex
NCOR1NCOA111497312569182 Reconstituted Complex
NCOR1SAP301149739702189 11013263 Co-purification; Reconstituted Complex
NCOR1SAP301143469702189 11013263 Co-purification; Reconstituted Complex
NCOR1HESX11149739751061 Reconstituted Complex
NCOR1HESX11143479751061 Reconstituted Complex
NCOR1HDAC311436810860984 10944117 11013263 11466315 11804585 11931768 12628926 14527417 14722073 16195251 16917504 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid
NCOR1HDAC311497310860984 10944117 11013263 11466315 11804585 11931768 12628926 14527417 14722073 16195251 16917504 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid
NCOR1NR1I211497318978041 Affinity Capture-Western; Two-hybrid
NCOR1NR1I211438018978041 Affinity Capture-Western; Two-hybrid
NCOR1BAZ1B11449716252006 Affinity Capture-Western
NCOR1BAZ1B11497316252006 Affinity Capture-Western
NCOR1CBFA2T211497316227606 Affinity Capture-Western
NCOR1CBFA2T211458616227606 Affinity Capture-Western
NCOR1COPS211497310877839 Reconstituted Complex
NCOR1COPS211472910877839 Reconstituted Complex
NCOR1NR1D11149738948627 Phenotypic Enhancement
NCOR1NR1D11149418948627 Phenotypic Enhancement
NR1D2NCOR11152998948627 9611234 Phenotypic Enhancement; Reconstituted Complex
NR1D2NCOR11149738948627 9611234 Phenotypic Enhancement; Reconstituted Complex
HDAC5NCOR111533110640275 10860984 11931768 Affinity Capture-Western; Reconstituted Complex
HDAC5NCOR111497310640275 10860984 11931768 Affinity Capture-Western; Reconstituted Complex
HDAC4NCOR111497310640275 10860984 11804585 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HDAC4NCOR111510610640275 10860984 11804585 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZMYND11NCOR111497310734313 Affinity Capture-Western
ZMYND11NCOR111598910734313 Affinity Capture-Western
NCOR2NCOR111497310944117 Co-fractionation
NCOR2NCOR111497410944117 Co-fractionation
TRIM28NCOR111497311013263 14761981 Affinity Capture-Western; Co-purification
TRIM28NCOR111545711013263 14761981 Affinity Capture-Western; Co-purification
SF3A1NCOR111558011013263 Co-purification
SF3A1NCOR111497311013263 Co-purification
SRCAPNCOR111497311013263 Co-purification
SRCAPNCOR111605811013263 Co-purification
SF3B3NCOR111497311013263 Co-purification
SF3B3NCOR111701611013263 Co-purification
SIN3ANCOR111497311430826 17210713 Affinity Capture-Western; Reconstituted Complex
SIN3ANCOR111743911430826 17210713 Affinity Capture-Western; Reconstituted Complex
TXNRD2NCOR111497311463857 18978041 Affinity Capture-Western; Reconstituted Complex
TXNRD2NCOR111583611463857 18978041 Affinity Capture-Western; Reconstituted Complex
HDAC7NCOR111497311466315 Affinity Capture-Western; Reconstituted Complex
HDAC7NCOR111961311466315 Affinity Capture-Western; Reconstituted Complex
HEY2NCOR111704511486045 Affinity Capture-Western; Reconstituted Complex
HEY2NCOR111497311486045 Affinity Capture-Western; Reconstituted Complex
TBL1XR1NCOR111497311931768 12628926 14527417 18202150 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
TBL1XR1NCOR112283411931768 12628926 14527417 18202150 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
TAB2NCOR111497312150997 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TAB2NCOR111674012150997 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HDAC9NCOR111497312590135 Affinity Capture-Western; Reconstituted Complex
HDAC9NCOR111508312590135 Affinity Capture-Western; Reconstituted Complex
NR1H3NCOR111497312663743 Two-hybrid
NR1H3NCOR111537312663743 Two-hybrid
SPENNCOR111497312897056 Reconstituted Complex
SPENNCOR111665512897056 Reconstituted Complex
TRIM33NCOR111497314527417 Affinity Capture-MS
TRIM33NCOR111962514527417 Affinity Capture-MS
KDM4ANCOR111503514527417 16024779 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex
KDM4ANCOR111497314527417 16024779 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex
ZBTB33NCOR111497314527417 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
ZBTB33NCOR111532714527417 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SNW1NCOR111497314985122 Reconstituted Complex; Two-hybrid
SNW1NCOR111659714985122 Reconstituted Complex; Two-hybrid
THAP7NCOR111497315561719 Affinity Capture-Western
THAP7NCOR112329815561719 Affinity Capture-Western
ATXN1LNCOR111497316121196 Two-hybrid
ATXN1LNCOR113117216121196 Two-hybrid
SAFB2NCOR111497316195251 Affinity Capture-Western
SAFB2NCOR111502216195251 Affinity Capture-Western
PRAM1NCOR111497316730330 Affinity Capture-Western
PRAM1NCOR112389416730330 Affinity Capture-Western
BAZ1ANCOR111497317519354 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BAZ1ANCOR111634717519354 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DZIP3NCOR111497318206970 Affinity Capture-Western
DZIP3NCOR111502118206970 Affinity Capture-Western
SIRT1NCOR111497318829436 Affinity Capture-Western; Reconstituted Complex
SIRT1NCOR111698318829436 Affinity Capture-Western; Reconstituted Complex
NR1H4NCOR111497318978041 Affinity Capture-Western
NR1H4NCOR111529618978041 Affinity Capture-Western
ZBTB7ANCOR111948819244234 Affinity Capture-Western
ZBTB7ANCOR111497319244234 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
NCOR1HTT12960310441327 HD interacts with N-CoR.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1349717
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-993'