AutismKB 2.0

Annotation Details for NCOR2


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Basic Information Top
Gene Symbol:NCOR2 ( CTG26,FLJ25011,N-CoR2,SMAP270,SMRT,SMRTE,SMRTE-tau,TNRC14,TRAC,TRAC-1,TRAC1 )
Gene Full Name: nuclear receptor corepressor 2
Band: 12q24.31
Quick LinksEntrez ID:9612; OMIM: 600848; Uniprot ID:NCOR2_HUMAN; ENSEMBL ID: ENSG00000196498; HGNC ID: 7673
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000118IBA-histone deacetylase complex-
GO:0000790IDA-nuclear chromatin20388878
GO:0005634IC-nucleus18052923
GO:0005634IDA-nucleus12628926
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016020IDA-membrane19946888
GO:0016363IDA-nuclear matrix21328542
GO:0016604IDA-nuclear body16030140
GO:0017053IDA-transcriptional repressor complex11804585
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003714IDA-transcription corepressor activity18052923
GO:0003714IMP-transcription corepressor activity12628926
GO:0005112IPI-Notch binding10713164
GO:0005515IPI-protein binding10395741
GO:0008134IBA-transcription factor binding-
GO:0016922IBA-ligand-dependent nuclear receptor binding-
GO:0042826IPI-histone deacetylase binding11804585
GO:0047485IPI-protein N-terminus binding16893456
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter12628926
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter-
GO:0006351IEA-transcription, DNA-templated-
GO:0019216TAS-regulation of lipid metabolic process-
GO:0072365IMP-regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter19955185
GO:1903799IMP-negative regulation of production of miRNAs involved in gene silencing by miRNA20388878
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NCOR2AKT111497416613989 Biochemical Activity; Reconstituted Complex
NCOR2AKT110671016613989 Biochemical Activity; Reconstituted Complex
NCOR2AR11497411923464 12441355 14593076 15062576 Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
NCOR2AR10686211923464 12441355 14593076 15062576 Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
NCOR2BCL61070769765306 10611298 10898795 11865059 14690607 15454082 15531890 Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybrid
NCOR2BCL61149749765306 10611298 10898795 11865059 14690607 15454082 15531890 Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybrid
NCOR2RUNX1T11149749819405 11113190 14982881 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2RUNX1T11073109819405 11113190 14982881 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2CEBPB11497415870285 Affinity Capture-Western; Reconstituted Complex
NCOR2CEBPB10748015870285 Affinity Capture-Western; Reconstituted Complex
NCOR2CHUK11497415494311 16382138 Biochemical Activity
NCOR2CHUK10756915494311 16382138 Biochemical Activity
NCOR2CREBBP11497417073437 Affinity Capture-Western
NCOR2CREBBP10777717073437 Affinity Capture-Western
NCOR2EP30010834717073437 Affinity Capture-Western
NCOR2EP30011497417073437 Affinity Capture-Western
NCOR2ESR11149749171229 14715875 Affinity Capture-Western; Reconstituted Complex
NCOR2ESR11084039171229 14715875 Affinity Capture-Western; Reconstituted Complex
NCOR2ESR211497414715875 Affinity Capture-Western
NCOR2ESR210840414715875 Affinity Capture-Western
NCOR2FOS11497410777532 Reconstituted Complex; Two-hybrid
NCOR2FOS10863610777532 Reconstituted Complex; Two-hybrid
NCOR2NR3C111497412011091 15870285 Affinity Capture-Western; Two-hybrid
NCOR2NR3C110916512011091 15870285 Affinity Capture-Western; Two-hybrid
NCOR2HDAC111497411013263 11739383 16481466 Affinity Capture-Western; Co-purification
NCOR2HDAC110931511013263 11739383 16481466 Affinity Capture-Western; Co-purification
NCOR2HDAC211497411013263 16481466 Affinity Capture-Western; Co-purification
NCOR2HDAC210931611013263 16481466 Affinity Capture-Western; Co-purification
NCOR2NR4A110940711559707 16002533 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2NR4A111497411559707 16002533 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2HNF4A11497412205093 Reconstituted Complex
NCOR2HNF4A10941412205093 Reconstituted Complex
NCOR2RBPJ10973611404076 11509665 Two-hybrid
NCOR2RBPJ11497411404076 11509665 Two-hybrid
NCOR2JUN10992810777532 Reconstituted Complex; Two-hybrid
NCOR2JUN11497410777532 Reconstituted Complex; Two-hybrid
NCOR2NFE2L211497415870285 Affinity Capture-Western; Reconstituted Complex
NCOR2NFE2L211085215870285 Affinity Capture-Western; Reconstituted Complex
NCOR2NFKB111085715494311 Co-localization
NCOR2NFKB111497415494311 Co-localization
NCOR2NFKBIA11497412589049 15536134 Affinity Capture-Western
NCOR2NFKBIA11085912589049 15536134 Affinity Capture-Western
NCOR2NFKBIB11497415536134 Reconstituted Complex
NCOR2NFKBIB11086015536134 Reconstituted Complex
NCOR2NFKBIE11497415536134 Reconstituted Complex
NCOR2NFKBIE11086115536134 Reconstituted Complex
NCOR2CNOT211497416712523 Two-hybrid
NCOR2CNOT211091016712523 Two-hybrid
NCOR2NR4A211098319144721 Affinity Capture-Western
NCOR2NR4A211497419144721 Affinity Capture-Western
NCOR2PGR11126010757795 12771131 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2PGR11497410757795 12771131 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2PML11138411430826 11585900 Affinity Capture-Western; Reconstituted Complex
NCOR2PML11497411430826 11585900 Affinity Capture-Western; Reconstituted Complex
NCOR2POU2F111497411134019 19617623 Affinity Capture-Western; Co-localization; Reconstituted Complex
NCOR2POU2F111144711134019 19617623 Affinity Capture-Western; Co-localization; Reconstituted Complex
NCOR2PPARA11497411845213 Co-crystal Structure
NCOR2PPARA11146111845213 Co-crystal Structure
NCOR2PPARD11497411867749 Affinity Capture-Western; Two-hybrid
NCOR2PPARD11146311867749 Affinity Capture-Western; Two-hybrid
NCOR2PPARG11497415681609 Co-localization
NCOR2PPARG11146415681609 Co-localization
NCOR2RARA1149749256429 9415406 10082574 11929748 17475621 Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
NCOR2RARA1118499256429 9415406 10082574 11929748 17475621 Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
NCOR2RELA11497410777532 12589049 16382138 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2RELA11190210777532 12589049 16382138 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2RXRA1149749415406 9878542 10082574 Reconstituted Complex; Two-hybrid
NCOR2RXRA1121689415406 9878542 10082574 Reconstituted Complex; Two-hybrid
NCOR2ATXN111221716121196 Two-hybrid
NCOR2ATXN111497416121196 Two-hybrid
NCOR2SKIL11238910049357 Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
NCOR2SKIL11497410049357 Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
NCOR2SMARCA411497410944117 Co-fractionation
NCOR2SMARCA411248110944117 Co-fractionation
NCOR2SP111255015878880 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2SP111497415878880 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2SRF11497410777532 Reconstituted Complex; Two-hybrid
NCOR2SRF11260010777532 Reconstituted Complex; Two-hybrid
NCOR2TBL1X11497410809664 10944117 12502735 12628926 Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex
NCOR2TBL1X11277010809664 10944117 12502735 12628926 Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex
NCOR2THRA1149749415406 Far Western
NCOR2THRA1129239415406 Far Western
NCOR2THRB1149749415406 9751500 9878542 11518802 19211732 Far Western; Reconstituted Complex; Two-hybrid
NCOR2THRB1129249415406 9751500 9878542 11518802 19211732 Far Western; Reconstituted Complex; Two-hybrid
NCOR2VDR1132649878542 12460926 Reconstituted Complex; Two-hybrid
NCOR2VDR1149749878542 12460926 Reconstituted Complex; Two-hybrid
NCOR2SF111336816002533 Affinity Capture-Western
NCOR2SF111497416002533 Affinity Capture-Western
NCOR2ZBTB161134989256429 9765306 11865059 14982881 16024608 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2ZBTB161149749256429 9765306 11865059 14982881 16024608 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2HIST1H4A11395512840002 15832170 Affinity Capture-Western; Reconstituted Complex
NCOR2HIST1H4A11497412840002 15832170 Affinity Capture-Western; Reconstituted Complex
NCOR2SAP3011434611013263 Co-purification
NCOR2SAP3011497411013263 Co-purification
NCOR2HDAC311436810809664 10860984 10944117 11013263 11804585 12205093 12502735 12628926 14527417 15837933 16481466 16924111 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex
NCOR2HDAC311497410809664 10860984 10944117 11013263 11804585 12205093 12502735 12628926 14527417 15837933 16481466 16924111 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex
NCOR2NR1I211438016144941 Reconstituted Complex
NCOR2NR1I211497416144941 Reconstituted Complex
NCOR2CIR111491611509665 Two-hybrid
NCOR2CIR111497411509665 Two-hybrid
NCOR2NCOR111497310944117 Co-fractionation
NCOR2NCOR111497410944117 Co-fractionation
HDAC4NCOR211510610640275 11804585 12205093 Affinity Capture-Western; Reconstituted Complex
HDAC4NCOR211497410640275 11804585 12205093 Affinity Capture-Western; Reconstituted Complex
SIN3ANCOR211743910640275 10944117 Co-fractionation; Reconstituted Complex
SIN3ANCOR211497410640275 10944117 Co-fractionation; Reconstituted Complex
HDAC5NCOR211533110640275 Reconstituted Complex; Two-hybrid
HDAC5NCOR211497410640275 Reconstituted Complex; Two-hybrid
SNW1NCOR211659710644367 10713164 14985122 Affinity Capture-Western; Two-hybrid
SNW1NCOR211497410644367 10713164 14985122 Affinity Capture-Western; Two-hybrid
NCOA6NCOR211669111158331 Two-hybrid
NCOA6NCOR211497411158331 Two-hybrid
SPENNCOR211665511331609 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SPENNCOR211497411331609 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HDAC7NCOR211961311466315 16956611 Affinity Capture-Western
HDAC7NCOR211497411466315 16956611 Affinity Capture-Western
INPP5KNCOR211972011509665 Two-hybrid
INPP5KNCOR211497411509665 Two-hybrid
HDAC10NCOR212381811739383 Affinity Capture-Western
HDAC10NCOR211497411739383 Affinity Capture-Western
IKZF1NCOR211560411959865 Affinity Capture-Western
IKZF1NCOR211497411959865 Affinity Capture-Western
ATXN1LNCOR213117216121196 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ATXN1LNCOR211497416121196 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BACH2NCOR212191317383980 Co-localization
BACH2NCOR211497417383980 Co-localization
FOXP1NCOR211798918347093 Affinity Capture-Western; Reconstituted Complex
FOXP1NCOR211497418347093 Affinity Capture-Western; Reconstituted Complex
ZBTB7ANCOR211948819244234 Affinity Capture-Western
ZBTB7ANCOR211497419244234 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1337080
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030616-81'