AutismKB 2.0

Annotation Details for TRAF4


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Basic Information Top
Gene Symbol:TRAF4 ( CART1,MLN62,RNF83 )
Gene Full Name: TNF receptor-associated factor 4
Band: 17q11.2
Quick LinksEntrez ID:9618; OMIM: 602464; Uniprot ID:TRAF4_HUMAN; ENSEMBL ID: ENSG00000076604; HGNC ID: 12034
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus18087216
GO:0005737IDA-cytoplasm16157600
GO:0005856IEA-cytoskeleton-
GO:0005886IEA-plasma membrane-
GO:0005923IEA-bicellular tight junction-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003677TAS-DNA binding7592751
GO:0005164IPI-tumor necrosis factor receptor binding11728344
GO:0005515IPI-protein binding10514511
GO:0008270IEA-zinc ion binding-
GO:0019901IEA-protein kinase binding-
GO:0031625IPI-ubiquitin protein ligase binding11279055
GO:0031996IPI-thioesterase binding11279055
GO:0042802IPI-identical protein binding25416956
GO:0050699IPI-WW domain binding19937093
GO ID Evidence Qualifier GO_term References
GO:0006915IEA-apoptotic process-
GO:0007165TAS-signal transduction7592751
GO:0007250IEA-activation of NF-kappaB-inducing kinase activity-
GO:0007585IEA-respiratory gaseous exchange-
GO:0030323IEA-respiratory tube development-
GO:0042981IEA-regulation of apoptotic process-
GO:0045860IDA-positive regulation of protein kinase activity16157600
GO:0046330IDA-positive regulation of JNK cascade16157600
GO:0090073IDA-positive regulation of protein homodimerization activity16157600
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TRAF4LTBR1149799626059 Reconstituted Complex
TRAF4LTBR1102339626059 Reconstituted Complex
TRAF4TRIM3711497911279055 Reconstituted Complex
TRAF4TRIM3711067811279055 Reconstituted Complex
TRAF4NGFR1149799626059 10514511 Affinity Capture-Western; Reconstituted Complex
TRAF4NGFR1108709626059 10514511 Affinity Capture-Western; Reconstituted Complex
TRAF4RPS6KB111497912801526 Affinity Capture-Western
TRAF4RPS6KB111211212801526 Affinity Capture-Western
TRAF4USP711497911279055 Reconstituted Complex
TRAF4USP711362211279055 Reconstituted Complex
NCF1TRAF411497912023963 Affinity Capture-Western
NCF1TRAF457572412023963 Affinity Capture-Western
SMURF1TRAF411497919937093 Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
SMURF1TRAF412141119937093 Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
No data
Gene Symbol Interactant Interaction ID References Description
TRAF4TGFB1I10383112023963 -
TRAF4TGFB1I10391512023963 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1202880
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040305-2'