AutismKB 2.0

Annotation Details for CELSR1


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Basic Information Top
Gene Symbol:CELSR1 ( CDHF9,DKFZp434P0729,FMI2,HFMI2,ME2 )
Gene Full Name: cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
Band: 22q13.31
Quick LinksEntrez ID:9620; OMIM: 604523; Uniprot ID:CELR1_HUMAN; ENSEMBL ID: ENSG00000075275; HGNC ID: 1850
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005886IDA-plasma membrane-
GO:0005887TAS-integral component of plasma membrane9339365
GO:0016021TAS-integral component of membrane10716726
GO ID Evidence Qualifier GO_term References
GO:0004888NAS-transmembrane signaling receptor activity9339365
GO:0004930NAS-G-protein coupled receptor activity9339365
GO:0005509IEA-calcium ion binding-
GO:0046983NAS-protein dimerization activity9339365
GO ID Evidence Qualifier GO_term References
GO:0001736ISS-establishment of planar polarity-
GO:0001764IEA-neuron migration-
GO:0001843ISS-neural tube closure-
GO:0001942IEA-hair follicle development-
GO:0007156IEA-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007186NAS-G-protein coupled receptor signaling pathway9339365
GO:0007266IEA-Rho protein signal transduction-
GO:0007417NAS-central nervous system development9339365
GO:0007417TAS-central nervous system development10716726
GO:0007626IEA-locomotory behavior-
GO:0009952IEA-anterior/posterior pattern specification-
GO:0032956IEA-regulation of actin cytoskeleton organization-
GO:0042060IEA-wound healing-
GO:0042249IEA-establishment of planar polarity of embryonic epithelium-
GO:0042472IEA-inner ear morphogenesis-
GO:0045176IEA-apical protein localization-
GO:0048105IEA-establishment of body hair planar orientation-
GO:0060071NAS-Wnt signaling pathway, planar cell polarity pathway24431302
GO:0060488IEA-orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis-
GO:0060489IEA-planar dichotomous subdivision of terminal units involved in lung branching morphogenesis-
GO:0060490IEA-lateral sprouting involved in lung morphogenesis-
GO:0090179IEA-planar cell polarity pathway involved in neural tube closure-
GO:0090251IEA-protein localization involved in establishment of planar polarity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CELSR1PSAP11498116169070 Two-hybrid
CELSR1PSAP11163916169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
CELSR1rs11575871, rs4823561, rs4823850 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1100883
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030616-78'