AutismKB 2.0

Annotation Details for ISG15


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Basic Information Top
Gene Symbol:ISG15 ( G1P2,IFI15,IP17,UCRP,hUCRP )
Gene Full Name: ISG15 ubiquitin-like modifier
Band: 1p36.33
Quick LinksEntrez ID:9636; OMIM: 147571; Uniprot ID:ISG15_HUMAN; ENSEMBL ID: ENSG00000187608; HGNC ID: 4053
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IDA-extracellular region22859821
GO:0005654TAS-nucleoplasm-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16189514
GO:0031386IEA-protein tag-
GO ID Evidence Qualifier GO_term References
GO:0019941IEA-modification-dependent protein catabolic process-
GO:0019985TAS-translesion synthesis-
GO:0030501ISS-positive regulation of bone mineralization-
GO:0031397IDA-negative regulation of protein ubiquitination18305167
GO:0032020IDA-ISG15-protein conjugation16122702
GO:0032020IMP-ISG15-protein conjugation22859821
GO:0032480TAS-negative regulation of type I interferon production-
GO:0032649IMP-regulation of interferon-gamma production22859821
GO:0034340IDA-response to type I interferon22859821
GO:0042742IMP-defense response to bacterium22859821
GO:0045071IMP-negative regulation of viral genome replication19357168
GO:0045648IEA-positive regulation of erythrocyte differentiation-
GO:0051607IMP-defense response to virus19357168
GO:0060337TAS-type I interferon signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ISG15ELF311499517353931 Affinity Capture-MS
ISG15ELF310831417353931 Affinity Capture-MS
ISG15ENO111499516884686 Affinity Capture-MS
ISG15ENO110833816884686 Affinity Capture-MS
ISG15ERCC211499516884686 Affinity Capture-MS
ISG15ERCC210838016884686 Affinity Capture-MS
ISG15FUT411499516884686 Affinity Capture-MS
ISG15FUT410880216884686 Affinity Capture-MS
ISG15HSPA411499516884686 Affinity Capture-MS
ISG15HSPA410954016884686 Affinity Capture-MS
ISG15NEDD411499518287095 Affinity Capture-Western
ISG15NEDD411081118287095 Affinity Capture-Western
ISG15SEPT211499518305167 Affinity Capture-Western
ISG15SEPT211081218305167 Affinity Capture-Western
ISG15PPM1B11499516884686 Affinity Capture-MS
ISG15PPM1B11149016884686 Affinity Capture-MS
ISG15RGS311499516884686 Affinity Capture-MS
ISG15RGS311193016884686 Affinity Capture-MS
ISG15UBA711499516189514 16884686 Affinity Capture-MS; Two-hybrid
ISG15UBA711316616189514 16884686 Affinity Capture-MS; Two-hybrid
ISG15UBE2D311499517719635 Affinity Capture-Western
ISG15UBE2D311317117719635 Affinity Capture-Western
ISG15TRIM2511350017069755 Affinity Capture-Western
ISG15TRIM2511499517069755 Affinity Capture-Western
USP18ISG1511499516189514 Two-hybrid
USP18ISG1511643016189514 Two-hybrid
STK38ISG1511499516884686 Affinity Capture-MS
STK38ISG1511645716884686 Affinity Capture-MS
DDX58ISG1511499517719635 Affinity Capture-Western
DDX58ISG1511712117719635 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1855694
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021211-1'