AutismKB 2.0

Annotation Details for ARHGEF10


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Basic Information Top
Gene Symbol:ARHGEF10 ( DKFZp686H0726,GEF10,MGC131664 )
Gene Full Name: Rho guanine nucleotide exchange factor (GEF) 10
Band: 8p23.3
Quick LinksEntrez ID:9639; OMIM: 608136; Uniprot ID:ARHGA_HUMAN; ENSEMBL ID: ENSG00000104728; HGNC ID: 14103
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005813IDA-centrosome19635168
GO:0005829NAS-cytosol16896804
GO ID Evidence Qualifier GO_term References
GO:0005089IDA-Rho guanyl-nucleotide exchange factor activity16896804
GO:0005515IPI-protein binding19635168
GO:0019894IPI-kinesin binding19635168
GO ID Evidence Qualifier GO_term References
GO:0022011IMP-myelination in peripheral nervous system14508709
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0051298IMP-centrosome duplication19635168
GO:0051496IMP-positive regulation of stress fiber assembly16896804
GO:0090307IMP-mitotic spindle assembly19635168
GO:0090630IDA-activation of GTPase activity16896804
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
WDR48ARHGEF1012164919615732 Affinity Capture-MS
WDR48ARHGEF1011499819615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
ARHGEF10rs11136439, rs11136442, rs11136444, rs2272611, rs2280823, rs3735866, rs3758013, rs3779707, rs4242549, rs4474061, rs4876268, rs7004405, rs7014895, rs7386016, rs997378, rs999545 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:2444453
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6210'