AutismKB 2.0

Annotation Details for FNIP1


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Basic Information Top
Gene Symbol:FNIP1 ( DKFZp686E18167,DKFZp781P0215,KIAA1961,MGC667 )
Gene Full Name: folliculin interacting protein 1
Band: 5q31.1
Quick LinksEntrez ID:96459; OMIM: 610594; Uniprot ID:FNIP1_HUMAN; ENSEMBL ID: ENSG00000217128; HGNC ID: 29418
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm17028174
GO ID Evidence Qualifier GO_term References
GO:0005085IDA-guanyl-nucleotide exchange factor activity22977732
GO:0005515IPI-protein binding17028174
GO:0042030IDA-ATPase inhibitor activity27353360
GO:0051087IDA-chaperone binding27353360
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter21209915
GO:0001932IDA-regulation of protein phosphorylation18663353
GO:0001934IMP-positive regulation of protein phosphorylation17028174
GO:0002327ISS-immature B cell differentiation-
GO:0002904ISS-positive regulation of B cell apoptotic process-
GO:0009267ISS-cellular response to starvation-
GO:0031334IDA-positive regulation of protein complex assembly25126726
GO:0031929IMP-TOR signaling17028174
GO:0032007ISS-negative regulation of TOR signaling-
GO:0033138IDA-positive regulation of peptidyl-serine phosphorylation19914239
GO:0043154ISS-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-
GO:0043547IEA-positive regulation of GTPase activity-
GO:2000973ISS-regulation of pro-B cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FNIP1HSP90AA112517517028174 Affinity Capture-MS
FNIP1HSP90AA110955217028174 Affinity Capture-MS
FNIP1PRKAA112517517028174 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
FNIP1PRKAA111154917028174 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
FNIP1PRKAA212517520562859 Affinity Capture-MS
FNIP1PRKAA211155020562859 Affinity Capture-MS
FNIP1PRKAB112517517028174 Affinity Capture-Western
FNIP1PRKAB111155117028174 Affinity Capture-Western
FNIP1PRKAG112517517028174 Affinity Capture-MS; Affinity Capture-Western
FNIP1PRKAG111155817028174 Affinity Capture-MS; Affinity Capture-Western
FLCNFNIP112517517028174 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
FLCNFNIP112836617028174 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2444668
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018