AutismKB 2.0

Annotation Details for CTR9


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Basic Information Top
Gene Symbol:CTR9 ( KIAA0155,SH2BP1,TSBP,p150,p150TSP )
Gene Full Name: Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Band: 11p15.4
Quick LinksEntrez ID:9646; OMIM: 609366; Uniprot ID:CTR9_HUMAN; ENSEMBL ID: ENSG00000198730; HGNC ID: 16850
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016593IDA-Cdc73/Paf1 complex16307923
GO:0016607IEA-nuclear speck-
GO:0035327ISS-transcriptionally active chromatin-
GO ID Evidence Qualifier GO_term References
GO:0000993IBA-RNA polymerase II core binding-
GO:0005515IPI-protein binding15923622
GO:0042169IEA-SH2 domain binding-
GO ID Evidence Qualifier GO_term References
GO:0000122ISS-negative regulation of transcription from RNA polymerase II promoter-
GO:0001711ISS-endodermal cell fate commitment-
GO:0001826IEA-inner cell mass cell differentiation-
GO:0001829IEA-trophectodermal cell differentiation-
GO:0001832IEA-blastocyst growth-
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0007259ISS-JAK-STAT cascade-
GO:0010390IDA-histone monoubiquitination16307923
GO:0016055IEA-Wnt signaling pathway-
GO:0016567TAS-protein ubiquitination-
GO:0019827IDA-stem cell population maintenance19345177
GO:0032968IDA-positive regulation of transcription elongation from RNA polymerase II promoter20178742
GO:0033523IDA-histone H2B ubiquitination16307923
GO:0045638IDA-negative regulation of myeloid cell differentiation20541477
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter20178742
GO:0051571IMP-positive regulation of histone H3-K4 methylation16024656
GO:0070102ISS-interleukin-6-mediated signaling pathway-
GO:0071222ISS-cellular response to lipopolysaccharide-
GO:0080182IMP-histone H3-K4 trimethylation16024656
GO:1900364IMP-negative regulation of mRNA polyadenylation19575011
GO:2000653IEA-regulation of genetic imprinting-
GO:2001162IMP-positive regulation of histone H3-K79 methylation16024656
GO:2001168IMP-positive regulation of histone H2B ubiquitination19575011
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTR9POLR2C11142818469135 Affinity Capture-Western
CTR9POLR2C11500418469135 Affinity Capture-Western
CTR9STAT311265117911113 Affinity Capture-Western
CTR9STAT311500417911113 Affinity Capture-Western
LEO1CTR912581715632063 18469135 Affinity Capture-MS; Affinity Capture-Western
LEO1CTR911500415632063 18469135 Affinity Capture-MS; Affinity Capture-Western
CDC73CTR912272415632063 18469135 Affinity Capture-MS; Affinity Capture-Western
CDC73CTR911500415632063 18469135 Affinity Capture-MS; Affinity Capture-Western
RTF1CTR911678018469135 Affinity Capture-MS
RTF1CTR911500418469135 Affinity Capture-MS
PAF1CTR911500418469135 Affinity Capture-MS; Affinity Capture-Western
PAF1CTR912008118469135 Affinity Capture-MS; Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109345
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018