AutismKB 2.0

Annotation Details for PPM1F


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Basic Information Top
Gene Symbol:PPM1F ( CAMKP,CaMKPase,FEM-2,KIAA0015,POPX2,hFEM-2 )
Gene Full Name: protein phosphatase, Mg2+/Mn2+ dependent, 1F
Band: 22q11.22
Quick LinksEntrez ID:9647; OMIM: NA; Uniprot ID:PPM1F_HUMAN; ENSEMBL ID: ENSG00000100034; HGNC ID: 19388
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol11559703
GO:0043234IDA-protein complex11864573
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0004722IDA-protein serine/threonine phosphatase activity11559703
GO:0004722IMP-protein serine/threonine phosphatase activity20016286
GO:0005515IPI-protein binding11559703
GO:0016791IDA-phosphatase activity15140879
GO:0033192IDA-calmodulin-dependent protein phosphatase activity11559703
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006469IDA-negative regulation of protein kinase activity11864573
GO:0010628IMP-positive regulation of gene expression20016286
GO:0010634IMP-positive regulation of epithelial cell migration20016286
GO:0010811IMP-positive regulation of cell-substrate adhesion20016286
GO:0016576IEA-histone dephosphorylation-
GO:0033137IDA-negative regulation of peptidyl-serine phosphorylation15140879
GO:0035690IDA-cellular response to drug20801214
GO:0035970IDA-peptidyl-threonine dephosphorylation11559703
GO:0043280IDA-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process11559703
GO:0044387IDA-negative regulation of protein kinase activity by regulation of protein phosphorylation15140879
GO:0045892IMP-negative regulation of transcription, DNA-templated20016286
GO:0045927IMP-positive regulation of growth20016286
GO:0050921IMP-positive regulation of chemotaxis20016286
GO:0051496IDA-positive regulation of stress fiber assembly11864573
GO:0051496IMP-positive regulation of stress fiber assembly20016286
GO:0051894IMP-positive regulation of focal adhesion assembly20016286
GO:0097193IDA-intrinsic apoptotic signaling pathway11559703
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PPM1FARHGEF711439311864573 Reconstituted Complex
PPM1FARHGEF711500511864573 Reconstituted Complex
FAM161APPM1F11500516169070 Two-hybrid
FAM161APPM1F12390916169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PPM1FD22S539 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1918464
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051128-2'