AutismKB 2.0

Annotation Details for NOS1AP


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Basic Information Top
Gene Symbol:NOS1AP ( 6330408P19Rik,CAPON,MGC138500 )
Gene Full Name: nitric oxide synthase 1 (neuronal) adaptor protein
Band: 1q23.3
Quick LinksEntrez ID:9722; OMIM: 605551; Uniprot ID:CAPON_HUMAN; ENSEMBL ID: ENSG00000198929; HGNC ID: 16859
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634ISS-nucleus24665357
GO:0005739ISS-mitochondrion19800018
GO:0005829ISS-cytosol24665357
GO:0005901ISScolocalizes_withcaveola19800018
GO:0030018ISS-Z disc19800018
GO:0030315ISScolocalizes_withT-tubule24665357
GO:0031965ISScolocalizes_withnuclear membrane24665357
GO:0033017ISS-sarcoplasmic reticulum membrane19800018
GO:0042383ISScolocalizes_withsarcolemma18337493
GO:0048471ISS-perinuclear region of cytoplasm18337493
GO:1902937ISScolocalizes_withinward rectifier potassium channel complex24665357
GO:1990454ISScolocalizes_withL-type voltage-gated calcium channel complex24665357
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0050998ISS-nitric-oxide synthase binding9459447
GO ID Evidence Qualifier GO_term References
GO:0003062IMP-regulation of heart rate by chemical signal19247217
GO:0010628ISS-positive regulation of gene expression18337493
GO:0010750ISS-positive regulation of nitric oxide mediated signal transduction18337493
GO:0042981NAS-regulation of apoptotic process20431962
GO:0045428NAS-regulation of nitric oxide biosynthetic process20431962
GO:0045429ISS-positive regulation of nitric oxide biosynthetic process18337493
GO:0050999NAS-regulation of nitric-oxide synthase activity20431962
GO:0051000ISS-positive regulation of nitric-oxide synthase activity18337493
GO:0060307IMP-regulation of ventricular cardiac muscle cell membrane repolarization19247217
GO:0060307ISS-regulation of ventricular cardiac muscle cell membrane repolarization18337493
GO:0098901ISS-regulation of cardiac muscle cell action potential18337493
GO:0098901TAS-regulation of cardiac muscle cell action potential24665357
GO:1901381ISS-positive regulation of potassium ion transmembrane transport18337493
GO:1901841ISS-regulation of high voltage-gated calcium channel activity18337493
GO:1902261ISS-positive regulation of delayed rectifier potassium channel activity18337493
GO:1902514ISS-regulation of calcium ion transmembrane transport via high voltage-gated calcium channel18337493
GO:1902514TAS-regulation of calcium ion transmembrane transport via high voltage-gated calcium channel24665357
GO:1903762ISS-positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization18337493
GO:2000170ISS-positive regulation of peptidyl-cysteine S-nitrosylation24665357
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NOS1APLRP111021510827173 Reconstituted Complex; Two-hybrid
NOS1APLRP111507110827173 Reconstituted Complex; Two-hybrid
NOS1APLRP211021610827173 Reconstituted Complex; Two-hybrid
NOS1APLRP211507110827173 Reconstituted Complex; Two-hybrid
NOS1APNOS11109059459447 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NOS1APNOS11150719459447 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NOS1APSYN111507111867766 Affinity Capture-Western; Reconstituted Complex
NOS1APSYN111271911867766 Affinity Capture-Western; Reconstituted Complex
NOS1APSYN211507111867766 Reconstituted Complex
NOS1APSYN211272011867766 Reconstituted Complex
NOS1APLRP811507110827173 Two-hybrid
NOS1APLRP811357910827173 Two-hybrid
NOS1APSYN311385711867766 Reconstituted Complex
NOS1APSYN311507111867766 Reconstituted Complex
RASD1NOS1AP11507111086993 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RASD1NOS1AP11966211086993 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
NOS1APD1S1679, D1S2675, NOS1AP_2bpSTR, NOS1AP_4bpSTR, rs10753746, rs10753784, rs10800404, rs10800405, rs10918776, rs10918856, rs10919080, rs1123005, rs1123015, rs11579080, rs11806859, rs12033217, rs12048222, rs12048687, rs12090585, rs12122048, rs12125293, rs12733821, rs12742393, rs1396224, rs1415263, rs1504430, rs1508262, rs1508263, rs1510289, rs1538018, rs1572495, rs164146, rs164147, rs17468951, rs1964052, rs1964082, rs2282396, rs2341744, rs2661818, rs347295, rs347306, rs347307, rs347313, rs348624, rs3751284, rs3751285, rs3924139, rs3927642, rs3934467, rs4145621, rs4306106, rs4592244, rs4656349, rs4656362, rs4657168, rs4657179, rs4657181, rs4657186, rs4657187, rs56120308, rs56153955, rs56387268, rs6427651, rs6680461, rs7521206, rs7528328, rs7546353, rs901662, rs905720, rs905721, rs945713 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1917979
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081024-1'