AutismKB 2.0

Annotation Details for DOCK4


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Basic Information Top
Gene Symbol:DOCK4 ( FLJ34238,KIAA0716,MGC134911,MGC134912 )
Gene Full Name: dedicator of cytokinesis 4
Band: 7q31.1
Quick LinksEntrez ID:9732; OMIM: 607679; Uniprot ID:DOCK4_HUMAN; ENSEMBL ID: ENSG00000128512; HGNC ID: 19192
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005730IDA-nucleolus-
GO:0005794IDA-Golgi apparatus-
GO:0005829IDA-cytosol20679435
GO:0005886IDA-plasma membrane-
GO:0016020IDA-membrane20679435
GO:0032420ISS-stereocilium16464467
GO:0032421ISS-stereocilium bundle16464467
GO ID Evidence Qualifier GO_term References
GO:0005085IEA-guanyl-nucleotide exchange factor activity-
GO:0005096IDA-GTPase activator activity16464467
GO:0005515IPI-protein binding16464467
GO:0017124IEA-SH3 domain binding-
GO:0030165IPI-PDZ domain binding16464467
GO:0030971IPI-receptor tyrosine kinase binding20679435
GO:0048365IDA-Rac GTPase binding16464467
GO ID Evidence Qualifier GO_term References
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0060326IMP-cell chemotaxis20679435
GO:1904694IMP-negative regulation of vascular smooth muscle contraction22158624
GO:1904754IMP-positive regulation of vascular associated smooth muscle cell migration22158624
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DOCK4HNRNPL11508117353931 Affinity Capture-MS
DOCK4HNRNPL10943217353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1918006
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060130-74'