AutismKB 2.0

Annotation Details for HDAC9


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Basic Information Top
Gene Symbol:HDAC9 ( DKFZp779K1053,HD7,HD7b,HD9,HDAC,HDAC7,HDAC7B,HDAC9B,HDAC9FL,HDRP,KIAA0744,MITR )
Gene Full Name: histone deacetylase 9
Band: 7p21.1
Quick LinksEntrez ID:9734; OMIM: 606543; Uniprot ID:HDAC9_HUMAN; ENSEMBL ID: ENSG00000048052; HGNC ID: 14065
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000118TAS-histone deacetylase complex12711221
GO:0005634IDA-nucleus12590135
GO:0005654TAS-nucleoplasm-
GO:0005667IDA-transcription factor complex15567413
GO:0005737IDA-cytoplasm12590135
GO:0005737TAS-cytoplasm12711221
GO:0035097ISS-histone methyltransferase complex-
GO ID Evidence Qualifier GO_term References
GO:0003714ISS-transcription corepressor activity-
GO:0004407IDA-histone deacetylase activity11535832
GO:0005080IPI-protein kinase C binding20188095
GO:0005515IPI-protein binding12590135
GO:0008134IDA-transcription factor binding11535832
GO:0008134IPI-transcription factor binding10748098
GO:0032041IEA-NAD-dependent histone deacetylase activity (H3-K14 specific)-
GO:0033558IDA-protein deacetylase activity11535832
GO:0042826IPI-histone deacetylase binding12590135
GO:0046872IEA-metal ion binding-
GO:0070491IDA-repressing transcription factor binding12590135
GO:0070491IPI-repressing transcription factor binding17360565
GO:0070491ISS-repressing transcription factor binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter10655483
GO:0001975IEA-response to amphetamine-
GO:0006351IEA-transcription, DNA-templated-
GO:0006954TAS-inflammatory response12711221
GO:0007507ISS-heart development-
GO:0016575IDA-histone deacetylation11535832
GO:0030182IEA-neuron differentiation-
GO:0030183TAS-B cell differentiation12711221
GO:0032869IDA-cellular response to insulin stimulus19303849
GO:0034983IDA-peptidyl-lysine deacetylation11535832
GO:0042113TAS-B cell activation12711221
GO:0045892IDA-negative regulation of transcription, DNA-templated11535832
GO:0048742ISS-regulation of skeletal muscle fiber development-
GO:0051153ISS-regulation of striated muscle cell differentiation-
GO:0070932IDA-histone H3 deacetylation12590135
GO:0070933IDA-histone H4 deacetylation12590135
GO:0090050IMP-positive regulation of cell migration involved in sprouting angiogenesis19351956
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HDAC9RUNX310731215138260 Affinity Capture-Western
HDAC9RUNX311508315138260 Affinity Capture-Western
HDAC9CTBP111508311022042 Reconstituted Complex
HDAC9CTBP110786911022042 Reconstituted Complex
HDAC9ESR110840319893013 Reconstituted Complex
HDAC9ESR111508319893013 Reconstituted Complex
HDAC9ETV610842112590135 Affinity Capture-Western
HDAC9ETV611508312590135 Affinity Capture-Western
HDAC9SFN10907215166223 Affinity Capture-Western
HDAC9SFN11508315166223 Affinity Capture-Western
HDAC9H3F3A11508317403666 Affinity Capture-MS
HDAC9H3F3A10927217403666 Affinity Capture-MS
HDAC9HDAC110931510487760 10655483 16611996 Affinity Capture-Western; Reconstituted Complex
HDAC9HDAC111508310487760 10655483 16611996 Affinity Capture-Western; Reconstituted Complex
HDAC9JUN10992816611996 Reconstituted Complex
HDAC9JUN11508316611996 Reconstituted Complex
HDAC9MEF2A11036910487761 10748098 Affinity Capture-Western; Reconstituted Complex
HDAC9MEF2A11508310487761 10748098 Affinity Capture-Western; Reconstituted Complex
HDAC9MEF2C11037220211142 20936779 Two-hybrid
HDAC9MEF2C11508320211142 20936779 Two-hybrid
HDAC9PKD111132715623513 15738054 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
HDAC9PKD111508315623513 15738054 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
HDAC9MAPK811158516611996 Affinity Capture-Western; Reconstituted Complex
HDAC9MAPK811508316611996 Affinity Capture-Western; Reconstituted Complex
HDAC9MAPK911508316611996 Affinity Capture-Western; Reconstituted Complex
HDAC9MAPK911158716611996 Affinity Capture-Western; Reconstituted Complex
HDAC9MAPK1011508316611996 Affinity Capture-Western; Reconstituted Complex
HDAC9MAPK1011158816611996 Affinity Capture-Western; Reconstituted Complex
HDAC9SUV39H111270612242305 Affinity Capture-Western; Reconstituted Complex
HDAC9SUV39H111508312242305 Affinity Capture-Western; Reconstituted Complex
HDAC9SYK11508316288017 Affinity Capture-Western; Reconstituted Complex
HDAC9SYK11271716288017 Affinity Capture-Western; Reconstituted Complex
HDAC9YWHAE11336315166223 20936779 Affinity Capture-Western; Two-hybrid
HDAC9YWHAE11508315166223 20936779 Affinity Capture-Western; Two-hybrid
HDAC9YWHAZ11508320936779 Two-hybrid
HDAC9YWHAZ11336620936779 Two-hybrid
HDAC9NUP21411508316356933 Affinity Capture-Western
HDAC9NUP21411371716356933 Affinity Capture-Western
HDAC9NRIP111508315060175 Reconstituted Complex
HDAC9NRIP111384315060175 Reconstituted Complex
HDAC9CAMK111508315166223 Affinity Capture-Western
HDAC9CAMK111410615166223 Affinity Capture-Western
HDAC9RFXANK11508315964851 Affinity Capture-Western; Reconstituted Complex
HDAC9RFXANK11418015964851 Affinity Capture-Western; Reconstituted Complex
HDAC9HDAC311436810655483 12590135 Affinity Capture-Western; Reconstituted Complex
HDAC9HDAC311508310655483 12590135 Affinity Capture-Western; Reconstituted Complex
HDAC9NCOR111497312590135 Affinity Capture-Western; Reconstituted Complex
HDAC9NCOR111508312590135 Affinity Capture-Western; Reconstituted Complex
HDAC9MORF4L211508314506250 Affinity Capture-Western
HDAC9MORF4L211500114506250 Affinity Capture-Western
HEY2HDAC911704511486045 Affinity Capture-Western
HEY2HDAC911508311486045 Affinity Capture-Western
SIN3AHDAC911508311959865 12590135 Affinity Capture-Western; Reconstituted Complex
SIN3AHDAC911743911959865 12590135 Affinity Capture-Western; Reconstituted Complex
CBX5HDAC911508312242305 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
CBX5HDAC911703012242305 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
HIST4H4HDAC911508312590135 Biochemical Activity
HIST4H4HDAC912573212590135 Biochemical Activity
HIST2H3AHDAC911508312590135 Biochemical Activity
HIST2H3AHDAC913061612590135 Biochemical Activity
SIN3BHDAC911508312590135 Reconstituted Complex
SIN3BHDAC911690112590135 Reconstituted Complex
HDAC4HDAC911508312590135 Reconstituted Complex
HDAC4HDAC911510612590135 Reconstituted Complex
MEF2BHDAC911508315567413 Co-crystal Structure
MEF2BHDAC993850915567413 Co-crystal Structure
ANKRA2HDAC911508315964851 Reconstituted Complex
ANKRA2HDAC912175815964851 Reconstituted Complex
FOXP3HDAC911508317360565 Affinity Capture-Western
FOXP3HDAC911917017360565 Affinity Capture-Western
HDAC9HDAC911508318332106 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1931221
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040109-7'