AutismKB 2.0

Annotation Details for SLK


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Basic Information Top
Gene Symbol:SLK ( KIAA0204,LOSK,MGC133067,STK2,bA16H23.1,se20-9 )
Gene Full Name: STE20-like kinase
Band: 10q24.33-q25.1
Quick LinksEntrez ID:9748; OMIM: NA; Uniprot ID:SLK_HUMAN; ENSEMBL ID: ENSG00000065613; HGNC ID: 11088
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm18287541
GO:0031252ISS-cell leading edge-
GO:0048471IDA-perinuclear region of cytoplasm26094769
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity18239682
GO:0004702IBA-signal transducer, downstream of receptor, with serine/threonine kinase activity-
GO:0005515IPI-protein binding25882817
GO:0005524IEA-ATP binding-
GO:0042802IPI-identical protein binding18239682
GO:0042803IDA-protein homodimerization activity18239682
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0006915IEA-apoptotic process-
GO:0023014IEA-signal transduction by protein phosphorylation-
GO:0030334IMP-regulation of cell migration26818812
GO:0030334ISS-regulation of cell migration-
GO:0031122IMP-cytoplasmic microtubule organization18287541
GO:0042981IDA-regulation of apoptotic process22203681
GO:0046777IDA-protein autophosphorylation18239682
GO:0051893IDA-regulation of focal adhesion assembly23128389
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SLKPDZK111120014531806 Reconstituted Complex; Two-hybrid
SLKPDZK111509614531806 Reconstituted Complex; Two-hybrid
KEAP1SLK11509619615732 Affinity Capture-MS
KEAP1SLK11515619615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
SLKrs805657 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:103241
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1684'