AutismKB 2.0

Annotation Details for FAM65B


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Basic Information Top
Gene Symbol:FAM65B ( C6orf32,DIFF40,DIFF48,KIAA0386,PL48 )
Gene Full Name: family with sequence similarity 65, member B
Band: 6p22.3-p21.32
Quick LinksEntrez ID:9750; OMIM: 611410; Uniprot ID:FA65B_HUMAN; ENSEMBL ID: ENSG00000111913; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm17150207
GO:0005739IEA-mitochondrion-
GO:0005856IDA-cytoskeleton17150207
GO:0016324IEA-apical plasma membrane-
GO:0030175IDA-filopodium17150207
GO:0032420ISS-stereocilium-
GO:0060171IEA-stereocilium membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding21988832
GO:0042802IEA-identical protein binding-
GO:0071889IDA-14-3-3 protein binding24687993
GO ID Evidence Qualifier GO_term References
GO:0007162IMP-negative regulation of cell adhesion23241886
GO:0007162ISS-negative regulation of cell adhesion-
GO:0007605IMP-sensory perception of sound24958875
GO:0035024IMP-negative regulation of Rho protein signal transduction23241886
GO:0035024ISS-negative regulation of Rho protein signal transduction-
GO:0045184IEA-establishment of protein localization-
GO:0045663IMP-positive regulation of myoblast differentiation17150207
GO:0048741IEA-skeletal muscle fiber development-
GO:0051260IEA-protein homooligomerization-
GO:0051491IMP-positive regulation of filopodium assembly17150207
GO:0060088IEA-auditory receptor cell stereocilium organization-
GO:0071260IEA-cellular response to mechanical stimulus-
GO:0090023ISS-positive regulation of neutrophil chemotaxis-
GO:1901741IMP-positive regulation of myoblast fusion17150207
GO:1903904IMP-negative regulation of establishment of T cell polarity23241886
GO:1905872ISS-negative regulation of protein localization to cell leading edge-
GO:1990869IDA-cellular response to chemokine23241886
GO:2000114ISS-regulation of establishment of cell polarity-
GO:2000391ISS-positive regulation of neutrophil extravasation-
GO:2000405IMP-negative regulation of T cell migration23241886
GO:2001107IMP-negative regulation of Rho guanyl-nucleotide exchange factor activity23241886
GO:2001107ISS-negative regulation of Rho guanyl-nucleotide exchange factor activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FAM65BYWHAG11336420936779 Two-hybrid
FAM65BYWHAG11509820936779 Two-hybrid
FAM65BYWHAZ11336620936779 Two-hybrid
FAM65BYWHAZ11509820936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2444879
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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