AutismKB 2.0

Annotation Details for MTSS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MTSS1 ( DKFZp781P2223,FLJ44694,KIAA0429,MIM,MIMA,MIMB )
Gene Full Name: metastasis suppressor 1
Band: 8q24.13
Quick LinksEntrez ID:9788; OMIM: 608486; Uniprot ID:MTSS1_HUMAN; ENSEMBL ID: ENSG00000170873; HGNC ID: 20443
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726NAS-ruffle12570871
GO:0005737TAS-cytoplasm12570871
GO:0015629IDA-actin cytoskeleton12570871
GO:0030139TAS-endocytic vesicle12570871
GO ID Evidence Qualifier GO_term References
GO:0003785IDA-actin monomer binding12570871
GO:0005102IPI-receptor binding12570871
GO:0005515IPI-protein binding15383276
GO:0042802IPI-identical protein binding14752106
GO ID Evidence Qualifier GO_term References
GO:0006928NAS-movement of cell or subcellular component12570871
GO:0007009IEA-plasma membrane organization-
GO:0007155NAS-cell adhesion12570871
GO:0007169TAS-transmembrane receptor protein tyrosine kinase signaling pathway12570871
GO:0030035NAS-microspike assembly12570871
GO:0030036TAS-actin cytoskeleton organization12082544
GO:0050680ISS-negative regulation of epithelial cell proliferation-
GO:0061333ISS-renal tubule morphogenesis-
GO:0071498ISS-cellular response to fluid shear stress-
GO:0072102ISS-glomerulus morphogenesis-
GO:0072160ISS-nephron tubule epithelial cell differentiation-
GO:2001013ISS-epithelial cell proliferation involved in renal tubule morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MTSS1RECQL511479716169070 Two-hybrid
MTSS1RECQL511513216169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2384818
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018