AutismKB 2.0

Annotation Details for RNF40


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Basic Information Top
Gene Symbol:RNF40 ( BRE1B,DKFZp686K191,KIAA0661,MGC13051,RBP95,STARING )
Gene Full Name: ring finger protein 40
Band: 16p11.2
Quick LinksEntrez ID:9810; OMIM: 607700; Uniprot ID:BRE1B_HUMAN; ENSEMBL ID: ENSG00000103549; HGNC ID: 16867
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000151IDA-ubiquitin ligase complex16307923
GO:0005634IDA-nucleus10944455
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005829IEA-cytosol-
GO:0016020IDA-membrane19946888
GO:0019898IEA-extrinsic component of membrane-
GO:0033503IDA-HULC complex19410543
GO:0043005ISS-neuron projection-
GO:0043679IEA-axon terminus-
GO ID Evidence Qualifier GO_term References
GO:0003730IDA-mRNA 3'-UTR binding19575011
GO:0004842IDAcontributes_toubiquitin-protein transferase activity16307923
GO:0005515IPI-protein binding10944455
GO:0017075IEA-syntaxin-1 binding-
GO:0031624IEA-ubiquitin conjugating enzyme binding-
GO:0031625IPI-ubiquitin protein ligase binding16307923
GO:0032403IEA-protein complex binding-
GO:0042803IPI-protein homodimerization activity10944455
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006511ISS-ubiquitin-dependent protein catabolic process-
GO:0007346IMPNOTregulation of mitotic cell cycle19575011
GO:0010390IDA-histone monoubiquitination16307923
GO:0016567TAS-protein ubiquitination-
GO:0033523IDA-histone H2B ubiquitination16307923
GO:0043434IEA-response to peptide hormone-
GO:1900364IMP-negative regulation of mRNA polyadenylation19575011
GO:1901800IEA-positive regulation of proteasomal protein catabolic process-
GO:1902916IEA-positive regulation of protein polyubiquitination-
GO:2001168IMP-positive regulation of histone H2B ubiquitination19575011
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RNF40NCBP111076616189514 Two-hybrid
RNF40NCBP111514916189514 Two-hybrid
RNF40STX1A11267612121982 Affinity Capture-Western; Reconstituted Complex
RNF40STX1A11514912121982 Affinity Capture-Western; Reconstituted Complex
RNF40UBE2L611467212121982 Affinity Capture-Western
RNF40UBE2L611514912121982 Affinity Capture-Western
ZNF451RNF4011514916189514 Two-hybrid
ZNF451RNF4011750216189514 Two-hybrid
SPRYD5RNF4012424816189514 Two-hybrid
SPRYD5RNF4011514916189514 Two-hybrid
USP15RNF4011528319615732 Affinity Capture-MS
USP15RNF4011514919615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2142048
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6607'