AutismKB 2.0

Annotation Details for ELMO1


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Basic Information Top
Gene Symbol:ELMO1 ( CED-12,CED12,ELMO-1,KIAA0281,MGC126406 )
Gene Full Name: engulfment and cell motility 1
Band: 7p14.2-p14.1
Quick LinksEntrez ID:9844; OMIM: 606420; Uniprot ID:ELMO1_HUMAN; ENSEMBL ID: ENSG00000155849; HGNC ID: 16286
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm11595183
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane11595183
GO:0016020IDA-membrane19946888
GO:0032045IDA-guanyl-nucleotide exchange factor complex12134158
GO ID Evidence Qualifier GO_term References
GO:0005085IDAcontributes_toguanyl-nucleotide exchange factor activity12134158
GO:0005515IPI-protein binding12029088
GO:0017124IPI-SH3 domain binding12029088
GO ID Evidence Qualifier GO_term References
GO:0006911IGI-phagocytosis, engulfment11595183
GO:0006915NAS-apoptotic process11595183
GO:0016477IEA-cell migration-
GO:0016601IGI-Rac protein signal transduction11595183
GO:0030036IGI-actin cytoskeleton organization11595183
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0048870IGI-cell motility11595183
GO:0050690TAS-regulation of defense response to virus by virus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ELMO1DOCK110812811595183 12134158 16495483 Affinity Capture-Western
ELMO1DOCK111518011595183 12134158 16495483 Affinity Capture-Western
ELMO1HCK11518012029088 Affinity Capture-Western; Reconstituted Complex
ELMO1HCK10930512029088 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2153044
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2069'