AutismKB 2.0

Annotation Details for PSMD6


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Basic Information Top
Gene Symbol:PSMD6 ( KIAA0107,Rpn7,S10,SGA-113M,p44S10 )
Gene Full Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
Band: 3p14.1
Quick LinksEntrez ID:9861; OMIM: NA; Uniprot ID:PSMD6_HUMAN; ENSEMBL ID: ENSG00000163636; HGNC ID: 9564
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000502IDA-proteasome complex17323924
GO:0005576TAS-extracellular region-
GO:0005654TAS-nucleoplasm-
GO:0005829TAS-cytosol-
GO:0005838IBA-proteasome regulatory particle-
GO:0022624ISS-proteasome accessory complex-
GO:0034774TAS-secretory granule lumen-
GO:0070062IDA-extracellular exosome23376485
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0016887NAS-ATPase activity10723133
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006508NAS-proteolysis10723133
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016579TAS-protein deubiquitination-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0043161IBA-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043312TAS-neutrophil degranulation-
GO:0043488TAS-regulation of mRNA stability-
GO:0043687TAS-post-translational protein modification-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PSMD6PSMA211165617353931 Affinity Capture-MS
PSMD6PSMA211519517353931 Affinity Capture-MS
PSMD6PSMB511519517353931 Affinity Capture-MS
PSMD6PSMB511166617353931 Affinity Capture-MS
PSMD6PSMC111519517353931 Affinity Capture-MS
PSMD6PSMC111167317353931 Affinity Capture-MS
PSMD6PSMC211519517353931 Affinity Capture-MS
PSMD6PSMC211167417353931 Affinity Capture-MS
PSMD6PSMC311519517353931 Affinity Capture-MS
PSMD6PSMC311167517353931 Affinity Capture-MS
PSMD6PSMC411519517353931 Affinity Capture-MS
PSMD6PSMC411167717353931 Affinity Capture-MS
PSMD6PSMC511519517353931 Affinity Capture-MS
PSMD6PSMC511167817353931 Affinity Capture-MS
PSMD6PSMC611519517353931 Affinity Capture-MS
PSMD6PSMC611167917353931 Affinity Capture-MS
PSMD6PSMD111519517353931 Affinity Capture-MS
PSMD6PSMD111168017353931 Affinity Capture-MS
PSMD6PSMD211519517353931 Affinity Capture-MS
PSMD6PSMD211168117353931 Affinity Capture-MS
PSMD6PSMD311519517353931 Affinity Capture-MS
PSMD6PSMD311168217353931 Affinity Capture-MS
PSMD6PSMD411519517353931 Affinity Capture-MS
PSMD6PSMD411168317353931 Affinity Capture-MS
PSMD6PSMD711519517353931 19615732 Affinity Capture-MS
PSMD6PSMD711168517353931 19615732 Affinity Capture-MS
PSMD6PSMD811519517353931 Affinity Capture-MS
PSMD6PSMD811168617353931 Affinity Capture-MS
PSMD6PSMD1011519517353931 Affinity Capture-MS
PSMD6PSMD1011168817353931 Affinity Capture-MS
PSMD6PSMD1111519517353931 Affinity Capture-MS
PSMD6PSMD1111168917353931 Affinity Capture-MS
PSMD6PSMD1211169017353931 Affinity Capture-MS
PSMD6PSMD1211519517353931 Affinity Capture-MS
PSMD6PSMD1311169117353931 Affinity Capture-MS
PSMD6PSMD1311519517353931 Affinity Capture-MS
PSMD6USP1411519519615732 Affinity Capture-MS
PSMD6USP1411455119615732 Affinity Capture-MS
PSMD6UBE3C11519512692129 Affinity Capture-Western
PSMD6UBE3C11504312692129 Affinity Capture-Western
UBAC1PSMD611519516227581 Affinity Capture-Western
UBAC1PSMD611569116227581 Affinity Capture-Western
PSMD14PSMD611519517353931 19615732 Affinity Capture-MS
PSMD14PSMD611550817353931 19615732 Affinity Capture-MS
PAAF1PSMD611519517353931 Affinity Capture-MS
PAAF1PSMD612319117353931 Affinity Capture-MS
TELO2PSMD611519517353931 Affinity Capture-MS
TELO2PSMD611522317353931 Affinity Capture-MS
SLX1BPSMD611519519596235 Affinity Capture-MS
SLX1BPSMD612247919596235 Affinity Capture-MS
USP20PSMD611607719615732 Affinity Capture-MS
USP20PSMD611519519615732 Affinity Capture-MS
UCHL5PSMD611519519615732 Affinity Capture-MS
UCHL5PSMD611950919615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1913663
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1038'