AutismKB 2.0

Annotation Details for MED24


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Basic Information Top
Gene Symbol:MED24 ( ARC100,CRSP100,CRSP4,DRIP100,KIAA0130,MGC8748,THRAP4,TRAP100,hTRAP100 )
Gene Full Name: mediator complex subunit 24
Band: 17q21.1
Quick LinksEntrez ID:9862; OMIM: 607000; Uniprot ID:MED24_HUMAN; ENSEMBL ID: ENSG00000008838; HGNC ID: 22963
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10235267
GO:0005654TAS-nucleoplasm-
GO:0016592IBA-mediator complex-
GO:0016592NAS-mediator complex9653119
GO ID Evidence Qualifier GO_term References
GO:0001104IDA-RNA polymerase II transcription cofactor activity10198638
GO:0003712IDA-transcription cofactor activity12218053
GO:0004872IDA-receptor activity12218053
GO:0005515IPI-protein binding24882805
GO:0030374NAS-ligand-dependent nuclear receptor transcription coactivator activity10235266
GO:0042809NAS-vitamin D receptor binding10235266
GO:0046966IDA-thyroid hormone receptor binding10198638
GO ID Evidence Qualifier GO_term References
GO:0006357IEA-regulation of transcription from RNA polymerase II promoter-
GO:0006367IDA-transcription initiation from RNA polymerase II promoter12218053
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0030518IDA-intracellular steroid hormone receptor signaling pathway11867769
GO:0030521IDA-androgen receptor signaling pathway12218053
GO:0045893IDA-positive regulation of transcription, DNA-templated10198638
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MED24PARP111519616204234 Affinity Capture-Western
MED24PARP110665216204234 Affinity Capture-Western
MED24AR11519619762545 Two-hybrid
MED24AR10686219762545 Two-hybrid
MED24BRCA111519615208681 Affinity Capture-MS; Affinity Capture-Western
MED24BRCA110714015208681 Affinity Capture-MS; Affinity Capture-Western
MED24CDK811519610198638 11867769 Affinity Capture-MS; Affinity Capture-Western
MED24CDK810745810198638 11867769 Affinity Capture-MS; Affinity Capture-Western
MED24ESR111519611867769 12837248 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MED24ESR110840311867769 12837248 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MED24ESR211519611867769 Reconstituted Complex
MED24ESR210840411867769 Reconstituted Complex
MED24HNF4A11519612101254 Reconstituted Complex
MED24HNF4A10941412101254 Reconstituted Complex
MED24SMAD111026112167862 Affinity Capture-Western
MED24SMAD111519612167862 Affinity Capture-Western
MED24SMAD211519612167862 Affinity Capture-Western
MED24SMAD211026212167862 Affinity Capture-Western
MED24SMAD311519612167862 Affinity Capture-Western
MED24SMAD311026312167862 Affinity Capture-Western
MED24PPARA1151969653119 Reconstituted Complex
MED24PPARA1114619653119 Reconstituted Complex
MED24PPARG1151969653119 Reconstituted Complex
MED24PPARG1114649653119 Reconstituted Complex
MED24MED11114659653119 15989967 Affinity Capture-MS; Affinity Capture-Western; Co-purification
MED24MED11151969653119 15989967 Affinity Capture-MS; Affinity Capture-Western; Co-purification
MED24RXRA1151969653119 Reconstituted Complex
MED24RXRA1121689653119 Reconstituted Complex
MED24SREBF111259810235267 Co-purification
MED24SREBF111519610235267 Co-purification
MED24THRA11519610198638 11117530 Affinity Capture-Western
MED24THRA11292310198638 11117530 Affinity Capture-Western
MED24VDR11326410198638 12837248 Affinity Capture-MS
MED24VDR11519610198638 12837248 Affinity Capture-MS
MED24TRRAP11519618418385 Co-purification
MED24TRRAP11390018418385 Co-purification
MED24MED2611519615175163 Affinity Capture-MS
MED24MED2611483115175163 Affinity Capture-MS
MED19MED2412855315175163 Affinity Capture-MS
MED19MED2411519615175163 Affinity Capture-MS
MED9MED2411519615175163 Affinity Capture-MS
MED9MED2412040315175163 Affinity Capture-MS
MED29MED2411519615175163 Affinity Capture-MS
MED29MED2412073415175163 Affinity Capture-MS
MED28MED2412321915175163 Affinity Capture-MS
MED28MED2411519615175163 Affinity Capture-MS
MED10MED2411519615175163 15989967 Affinity Capture-MS
MED10MED2412397415175163 15989967 Affinity Capture-MS
MED30MED2411519615989967 Affinity Capture-Western
MED30MED2412470715989967 Affinity Capture-Western
BRD4MED2411703616109376 Affinity Capture-MS
BRD4MED2411519616109376 Affinity Capture-MS
RPAP2MED2411519617643375 Affinity Capture-MS
RPAP2MED2412295917643375 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1344385
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2341'