AutismKB 2.0

Annotation Details for SETDB1


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Basic Information Top
Gene Symbol:SETDB1 ( ESET,H3-K9-HMTase4,KG1T,KIAA0067,KMT1E )
Gene Full Name: SET domain, bifurcated 1
Band: 1q21.3
Quick LinksEntrez ID:9869; OMIM: 604396; Uniprot ID:SETB1_HUMAN; ENSEMBL ID: ENSG00000143379; HGNC ID: 10761
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003682IDA-chromatin binding27029610
GO:0005515IPI-protein binding16682412
GO:0008270IEA-zinc ion binding-
GO:0018024IEA-histone-lysine N-methyltransferase activity-
GO:1990841IDA-promoter-specific chromatin binding24623306
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0007265IMP-Ras protein signal transduction24623306
GO:0033273IEA-response to vitamin-
GO:0034968IEA-histone lysine methylation-
GO:0045471IEA-response to ethanol-
GO:0090309IMP-positive regulation of methylation-dependent chromatin silencing24623306
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SETDB1APC11520220936779 Two-hybrid
SETDB1APC10682120936779 Two-hybrid
SETDB1ASAH111520216169070 Two-hybrid
SETDB1ASAH110692016169070 Two-hybrid
SETDB1CDK411520216169070 Two-hybrid
SETDB1CDK410745416169070 Two-hybrid
SETDB1DAP11520216169070 Two-hybrid
SETDB1DAP10798116169070 Two-hybrid
SETDB1TRDMT111520216169070 Two-hybrid
SETDB1TRDMT110812416169070 Two-hybrid
SETDB1DNMT3A11520216682412 Affinity Capture-Western
SETDB1DNMT3A10812516682412 Affinity Capture-Western
SETDB1DNMT3B11520216682412 Affinity Capture-Western
SETDB1DNMT3B10812616682412 Affinity Capture-Western
SETDB1ERH11520216169070 Two-hybrid
SETDB1ERH10839016169070 Two-hybrid
SETDB1GPS211520216169070 Two-hybrid
SETDB1GPS210913216169070 Two-hybrid
SETDB1HDAC211520212398767 Affinity Capture-Western
SETDB1HDAC210931612398767 Affinity Capture-Western
SETDB1HMOX211520216169070 Two-hybrid
SETDB1HMOX210940616169070 Two-hybrid
SETDB1MBD111520215327775 17066076 Affinity Capture-Western; Two-hybrid
SETDB1MBD111032215327775 17066076 Affinity Capture-Western; Two-hybrid
SETDB1PAFAH1B311520216169070 Two-hybrid
SETDB1PAFAH1B311108716169070 Two-hybrid
SETDB1PCNA11520215327775 Affinity Capture-Western
SETDB1PCNA11114215327775 Affinity Capture-Western
SETDB1SERPINB911520216169070 Two-hybrid
SETDB1SERPINB911129016169070 Two-hybrid
SETDB1POU5F111520219884257 Affinity Capture-Western
SETDB1POU5F111145619884257 Affinity Capture-Western
SETDB1PPA111520216169070 Two-hybrid
SETDB1PPA111146016169070 Two-hybrid
SETDB1PPARG11520217952062 Reconstituted Complex
SETDB1PPARG11146417952062 Reconstituted Complex
SETDB1PPP1R811520216169070 Two-hybrid
SETDB1PPP1R811150316169070 Two-hybrid
SETDB1PSMD1111520216169070 Two-hybrid
SETDB1PSMD1111168916169070 Two-hybrid
SETDB1PTPRS11520216169070 Two-hybrid
SETDB1PTPRS11176616169070 Two-hybrid
SETDB1S100A1011520216169070 Two-hybrid
SETDB1S100A1011218916169070 Two-hybrid
SETDB1SAT111520216169070 Two-hybrid
SETDB1SAT111221016169070 Two-hybrid
SETDB1SUMO211249719394292 Affinity Capture-MS
SETDB1SUMO211520219394292 Affinity Capture-MS
SETDB1SULT1E111520216169070 Two-hybrid
SETDB1SULT1E111266016169070 Two-hybrid
SETDB1TAT11520218498648 Affinity Capture-Western; Reconstituted Complex
SETDB1TAT11276118498648 Affinity Capture-Western; Reconstituted Complex
SETDB1TK111520216169070 Two-hybrid
SETDB1TK111293816169070 Two-hybrid
SETDB1TPI111520216169070 Two-hybrid
SETDB1TPI111302016169070 Two-hybrid
SETDB1TTR11520216169070 Two-hybrid
SETDB1TTR11312716169070 Two-hybrid
SETDB1UBE2I11520220936779 Two-hybrid
SETDB1UBE2I11317720936779 Two-hybrid
SETDB1ZNF2411520216169070 Two-hybrid
SETDB1ZNF2411340316169070 Two-hybrid
SETDB1BAT311520216169070 Two-hybrid
SETDB1BAT311364716169070 Two-hybrid
SETDB1CHAF1B11520219498464 Affinity Capture-MS
SETDB1CHAF1B11384619498464 Affinity Capture-MS
SETDB1USP1111520216169070 Two-hybrid
SETDB1USP1111386616169070 Two-hybrid
SETDB1HIST1H3A11394611252719 Biochemical Activity
SETDB1HIST1H3A11520211252719 Biochemical Activity
SETDB1BHLHE4011520216169070 Two-hybrid
SETDB1BHLHE4011412316169070 Two-hybrid
SETDB1PRKRA11520216169070 Two-hybrid
SETDB1PRKRA11414316169070 Two-hybrid
SETDB1TSC22D111437416169070 Two-hybrid
SETDB1TSC22D111520216169070 Two-hybrid
SETDB1HSPB311520216169070 Two-hybrid
SETDB1HSPB311447016169070 Two-hybrid
SETDB1AIFM111520216169070 Two-hybrid
SETDB1AIFM111457916169070 Two-hybrid
SETDB1CDYL11520219061646 Affinity Capture-MS
SETDB1CDYL11481819061646 Affinity Capture-MS
SETDB1GSTO111520216169070 Two-hybrid
SETDB1GSTO111483616169070 Two-hybrid
SETDB1MAD2L1BP11520216169070 Two-hybrid
SETDB1MAD2L1BP11495516169070 Two-hybrid
SETDB1ULK211520216169070 Two-hybrid
SETDB1ULK211505816169070 Two-hybrid
TRIM28SETDB111520211959841 Affinity Capture-MS; Two-hybrid
TRIM28SETDB111545711959841 Affinity Capture-MS; Two-hybrid
HIST4H4SETDB112573211959841 Reconstituted Complex
HIST4H4SETDB111520211959841 Reconstituted Complex
HIST2H3ASETDB113061611959841 Reconstituted Complex
HIST2H3ASETDB111520211959841 Reconstituted Complex
SIN3BSETDB111520212398767 Affinity Capture-Western
SIN3BSETDB111690112398767 Affinity Capture-Western
SIN3ASETDB111520212398767 Affinity Capture-Western
SIN3ASETDB111743912398767 Affinity Capture-Western
SUZ12SETDB111520214536086 Co-purification
SUZ12SETDB111705914536086 Co-purification
CHAF1ASETDB111520215327775 19498464 Affinity Capture-MS; Affinity Capture-Western
CHAF1ASETDB111534915327775 19498464 Affinity Capture-MS; Affinity Capture-Western
ATF7IPSETDB112084915691849 Affinity Capture-Western; Reconstituted Complex
ATF7IPSETDB111520215691849 Affinity Capture-Western; Reconstituted Complex
ATF7IP2SETDB112309715691849 Affinity Capture-Western; Reconstituted Complex
ATF7IP2SETDB111520215691849 Affinity Capture-Western; Reconstituted Complex
TOB1SETDB111520216169070 Two-hybrid
TOB1SETDB111544316169070 Two-hybrid
TXNDC9SETDB111520216169070 Two-hybrid
TXNDC9SETDB111548716169070 Two-hybrid
DLEU1SETDB111520216169070 Two-hybrid
DLEU1SETDB111558916169070 Two-hybrid
SLC38A3SETDB111520216169070 Two-hybrid
SLC38A3SETDB111618716169070 Two-hybrid
PGAM5SETDB112815416169070 Two-hybrid
PGAM5SETDB111520216169070 Two-hybrid
THAP8SETDB112826916169070 Two-hybrid
THAP8SETDB111520216169070 Two-hybrid
KDM1ASETDB111520216169070 Two-hybrid
KDM1ASETDB111666716169070 Two-hybrid
TARDBPSETDB111520216169070 Two-hybrid
TARDBPSETDB111700316169070 Two-hybrid
POLA2SETDB111520216169070 Two-hybrid
POLA2SETDB111717616169070 Two-hybrid
MOBKL3SETDB111520216169070 Two-hybrid
MOBKL3SETDB111736916169070 Two-hybrid
NIPSNAP3ASETDB111520216169070 Two-hybrid
NIPSNAP3ASETDB111743216169070 Two-hybrid
TRBV2SETDB111520216169070 Two-hybrid
TRBV2SETDB111847016169070 Two-hybrid
CCDC106SETDB111520216169070 Two-hybrid
CCDC106SETDB111895216169070 Two-hybrid
ECSITSETDB111520216169070 Two-hybrid
ECSITSETDB111944616169070 Two-hybrid
TOLLIPSETDB111520216169070 Two-hybrid
TOLLIPSETDB111997816169070 Two-hybrid
GIPC2SETDB112016716169070 Two-hybrid
GIPC2SETDB111520216169070 Two-hybrid
PHF10SETDB112056216169070 Two-hybrid
PHF10SETDB111520216169070 Two-hybrid
BRIX1SETDB112058616169070 Two-hybrid
BRIX1SETDB111520216169070 Two-hybrid
BTBD2SETDB112077816169070 Two-hybrid
BTBD2SETDB111520216169070 Two-hybrid
ZFP64SETDB112085316169070 Two-hybrid
ZFP64SETDB111520216169070 Two-hybrid
PCDHA4SETDB112108416169070 Two-hybrid
PCDHA4SETDB111520216169070 Two-hybrid
OLFML3SETDB112126816169070 Two-hybrid
OLFML3SETDB111520216169070 Two-hybrid
CBX8SETDB111520216169070 Two-hybrid
CBX8SETDB112148716169070 Two-hybrid
PLEKHA4SETDB112169716169070 Two-hybrid
PLEKHA4SETDB111520216169070 Two-hybrid
TRIB3SETDB112175616169070 Two-hybrid
TRIB3SETDB111520216169070 Two-hybrid
C11orf1SETDB112228616169070 Two-hybrid
C11orf1SETDB111520216169070 Two-hybrid
MRPL44SETDB112238916169070 Two-hybrid
MRPL44SETDB111520216169070 Two-hybrid
CRELD1SETDB112245816169070 Two-hybrid
CRELD1SETDB111520216169070 Two-hybrid
ORAI2SETDB112319216169070 Two-hybrid
ORAI2SETDB111520216169070 Two-hybrid
QTRT1SETDB111520216169070 Two-hybrid
QTRT1SETDB112362316169070 Two-hybrid
FLYWCH1SETDB112398316169070 Two-hybrid
FLYWCH1SETDB111520216169070 Two-hybrid
RNF10SETDB111520216169070 Two-hybrid
RNF10SETDB111524916169070 Two-hybrid
NLKSETDB111520217952062 Affinity Capture-Western; Co-purification
NLKSETDB111968517952062 Affinity Capture-Western; Co-purification
ESCO2SETDB112760518501190 Affinity Capture-Western
ESCO2SETDB111520218501190 Affinity Capture-Western
CBX5SETDB111520219498464 Affinity Capture-MS
CBX5SETDB111703019498464 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1934229
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2421'