AutismKB 2.0

Annotation Details for NUAK1


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Basic Information Top
Gene Symbol:NUAK1 ( ARK5,KIAA0537 )
Gene Full Name: NUAK family, SNF1-like kinase, 1
Band: 12q23.3
Quick LinksEntrez ID:9891; OMIM: 608130; Uniprot ID:NUAK1_HUMAN; ENSEMBL ID: ENSG00000074590; HGNC ID: 14311
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus21317932
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm21317932
GO:0015630IDA-microtubule cytoskeleton-
GO ID Evidence Qualifier GO_term References
GO:0002039IPI-p53 binding21317932
GO:0004674IDA-protein serine/threonine kinase activity19927127
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding19927127
GO:0005524IEA-ATP binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006468IDA-protein phosphorylation25329316
GO:0006974IEA-cellular response to DNA damage stimulus-
GO:0007155IEA-cell adhesion-
GO:0030155IDA-regulation of cell adhesion20354225
GO:0035507IDA-regulation of myosin-light-chain-phosphatase activity20354225
GO:0035556IBA-intracellular signal transduction-
GO:0042127TAS-regulation of cell proliferation21317932
GO:1901796TAS-regulation of signal transduction by p53 class mediator-
GO:2000772IDA-regulation of cellular senescence19927127
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NUAK1IGHA210971517353931 Affinity Capture-MS
NUAK1IGHA211522117353931 Affinity Capture-MS
NUAK1PRKAR1A11522117353931 Affinity Capture-MS
NUAK1PRKAR1A11155917353931 Affinity Capture-MS
NUAK1PRPSAP111161817353931 Affinity Capture-MS
NUAK1PRPSAP111522117353931 Affinity Capture-MS
NUAK1S100A811218717353931 Affinity Capture-MS
NUAK1S100A811522117353931 Affinity Capture-MS
NUAK1S100A911218817353931 Affinity Capture-MS
NUAK1S100A911522117353931 Affinity Capture-MS
NUAK1UBC11316418254724 Affinity Capture-Western; Reconstituted Complex
NUAK1UBC11522118254724 Affinity Capture-Western; Reconstituted Complex
NUAK1USP9X11386718254724 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
NUAK1USP9X11522118254724 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
KRT77NUAK113190317353931 Affinity Capture-MS
KRT77NUAK111522117353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1925226
  • Data Attributes: HomoloGene calculated
No data