AutismKB 2.0

Annotation Details for ARHGAP44


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Basic Information Top
Gene Symbol:ARHGAP44 ( KIAA0672,NPC-A-10,RICH2 )
Gene Full Name: Rho GTPase activating protein 44
Band: 17p12
Quick LinksEntrez ID:9912; OMIM: NA; Uniprot ID:RHG44_HUMAN; ENSEMBL ID: ENSG00000006740; HGNC ID: 29096
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0030054IEA-cell junction-
GO:0031256IDA-leading edge membrane22750946
GO:0043197IEA-dendritic spine-
GO:0055037IEA-recycling endosome-
GO ID Evidence Qualifier GO_term References
GO:0005096TAS-GTPase activator activity-
GO:0005515IPI-protein binding19273615
GO:0005543IDA-phospholipid binding22750946
GO:0048365IEA-Rac GTPase binding-
GO ID Evidence Qualifier GO_term References
GO:0006887IEA-exocytosis-
GO:0007165IEA-signal transduction-
GO:0032956IEA-regulation of actin cytoskeleton organization-
GO:0035021IEA-negative regulation of Rac protein signal transduction-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0061001IEA-regulation of dendritic spine morphogenesis-
GO:0098886IEA-modification of dendritic spine-
GO:0098887IEA-neurotransmitter receptor transport, endosome to postsynaptic membrane-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ARHGAP44CDC4211524111431473 Biochemical Activity
ARHGAP44CDC4210743311431473 Biochemical Activity
ARHGAP44RAC111524111431473 Biochemical Activity
ARHGAP44RAC111181711431473 Biochemical Activity
HN1ARHGAP4411524116169070 Two-hybrid
HN1ARHGAP4411933816169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2144423
  • Data Attributes: HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018