AutismKB 2.0

Annotation Details for ARNT2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ARNT2 ( KIAA0307,bHLHe1 )
Gene Full Name: aryl-hydrocarbon receptor nuclear translocator 2
Band: 15q25.1
Quick LinksEntrez ID:9915; OMIM: 606036; Uniprot ID:ARNT2_HUMAN; ENSEMBL ID: ENSG00000172379; HGNC ID: 16876
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12239177
GO:0005654TAS-nucleoplasm-
GO:0005667IEA-transcription factor complex-
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000981IDA-RNA polymerase II transcription factor activity, sequence-specific DNA binding24465693
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003700ISS-transcription factor activity, sequence-specific DNA binding-
GO:0005515IPI-protein binding24465693
GO:0017162ISS-aryl hydrocarbon receptor binding-
GO:0046982IDA-protein heterodimerization activity24465693
GO:0046982IPI-protein heterodimerization activity12239177
GO:0046982ISS-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001666IDA-response to hypoxia12239177
GO:0001701ISS-in utero embryonic development-
GO:0006355IDA-regulation of transcription, DNA-templated11782478
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0006805TAS-xenobiotic metabolic process-
GO:0007417ISS-central nervous system development-
GO:0007420IMP-brain development24022475
GO:0008284IEA-positive regulation of cell proliferation-
GO:0032355IEA-response to estradiol-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter24465693
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ARNT2EPAS110834820211142 Two-hybrid
ARNT2EPAS111524420211142 Two-hybrid
ARNT2SIM211524414701734 Two-hybrid
ARNT2SIM211238414701734 Two-hybrid
NPAS4ARNT211524414701734 Two-hybrid
NPAS4ARNT212933514701734 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107188
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001207-3'