AutismKB 2.0

Annotation Details for CDC25B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDC25B ( - )
Gene Full Name: cell division cycle 25 homolog B (S. pombe)
Band: 20p13
Quick LinksEntrez ID:994; OMIM: 116949; Uniprot ID:MPIP2_HUMAN; ENSEMBL ID: ENSG00000101224; HGNC ID: 1726
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000922IDA-spindle pole15908796
GO:0005654TAS-nucleoplasm-
GO:0005813IDA-centrosome15908796
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004721TAS-phosphoprotein phosphatase activity-
GO:0004725TAS-protein tyrosine phosphatase activity9188863
GO:0005515IPI-protein binding7644510
GO:0019901IPI-protein kinase binding12400006
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle12400006
GO:0000278TAS-mitotic cell cycle9188863
GO:0001556IEA-oocyte maturation-
GO:0006468IDA-protein phosphorylation17332740
GO:0007144IEA-female meiosis I-
GO:0008284TAS-positive regulation of cell proliferation8276402
GO:0032467IMP-positive regulation of cytokinesis17332740
GO:0035335IEA-peptidyl-tyrosine dephosphorylation-
GO:0045860IEA-positive regulation of protein kinase activity-
GO:0045931IMP-positive regulation of mitotic cell cycle17332740
GO:0051301IEA-cell division-
GO:1902751IEA-positive regulation of cell cycle G2/M phase transition-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDC25BAR10742912569365 Reconstituted Complex
CDC25BAR10686212569365 Reconstituted Complex
YWHABCDC25B1133617644510 10713667 Reconstituted Complex; Two-hybrid
YWHABCDC25B1074297644510 10713667 Reconstituted Complex; Two-hybrid
YWHAECDC25B1133637644510 10713667 Reconstituted Complex; Two-hybrid
YWHAECDC25B1074297644510 10713667 Reconstituted Complex; Two-hybrid
CDK2CDC25B1074527644510 Two-hybrid
CDK2CDC25B1074297644510 Two-hybrid
CHEK1CDC25B1075369278511 Biochemical Activity; Reconstituted Complex
CHEK1CDC25B1074299278511 Biochemical Activity; Reconstituted Complex
YWHAHCDC25B11336510713667 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAHCDC25B10742910713667 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAQCDC25B11616810713667 Reconstituted Complex
YWHAQCDC25B10742910713667 Reconstituted Complex
YWHAZCDC25B11336610713667 Reconstituted Complex; Two-hybrid
YWHAZCDC25B10742910713667 Reconstituted Complex; Two-hybrid
MAPK14CDC25B10781911333986 Biochemical Activity; Reconstituted Complex
MAPK14CDC25B10742911333986 Biochemical Activity; Reconstituted Complex
ESR1CDC25B10742911689696 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ESR1CDC25B10840311689696 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PGRCDC25B11126011689696 Reconstituted Complex
PGRCDC25B10742911689696 Reconstituted Complex
KAT2BCDC25B11437511689696 Reconstituted Complex
KAT2BCDC25B10742911689696 Reconstituted Complex
MELKCDC25B11517112400006 Affinity Capture-Western; Reconstituted Complex
MELKCDC25B10742912400006 Affinity Capture-Western; Reconstituted Complex
CSNK2A1CDC25B10784112527891 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CSNK2A1CDC25B10742912527891 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
FOXM1CDC25B10742915024056 Affinity Capture-Western
FOXM1CDC25B10859415024056 Affinity Capture-Western
PHB2CDC25B11645917353931 Affinity Capture-MS
PHB2CDC25B10742917353931 Affinity Capture-MS
KRT31CDC25B11007917353931 Affinity Capture-MS
KRT31CDC25B10742917353931 Affinity Capture-MS
KRT35CDC25B11008417353931 Affinity Capture-MS
KRT35CDC25B10742917353931 Affinity Capture-MS
KRT85CDC25B11008917353931 Affinity Capture-MS
KRT85CDC25B10742917353931 Affinity Capture-MS
FBXW11CDC25B10742919615732 Affinity Capture-MS
FBXW11CDC25B11688719615732 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
YWHABCDC25B3005987644510 14-3-3-beta interacts with cdc25B.
YWHAECDC25B3005997644510 14-3-3-epsilon interacts with cdc25B.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99701
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved