AutismKB 2.0

Annotation Details for USP15


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Basic Information Top
Gene Symbol:USP15 ( KIAA0529,MGC131982,MGC149838,MGC74854,UNPH4 )
Gene Full Name: ubiquitin specific peptidase 15
Band: 12q14.1
Quick LinksEntrez ID:9958; OMIM: 604731; Uniprot ID:UBP15_HUMAN; ENSEMBL ID: ENSG00000135655; HGNC ID: 12613
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21947082
GO:0005737IDA-cytoplasm21947082
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004197IMP-cysteine-type endopeptidase activity21947082
GO:0004843IDA-thiol-dependent ubiquitin-specific protease activity16005295
GO:0005160IPI-transforming growth factor beta receptor binding22344298
GO:0005515IPI-protein binding24526689
GO:0036459IDA-thiol-dependent ubiquitinyl hydrolase activity21947082
GO:0036459TAS-thiol-dependent ubiquitinyl hydrolase activity-
GO:0042802IPI-identical protein binding22001210
GO:0046332IPI-SMAD binding21947082
GO:0061649IDA-ubiquitin modification-dependent histone binding24526689
GO ID Evidence Qualifier GO_term References
GO:0006511IEA-ubiquitin-dependent protein catabolic process-
GO:0007179IDA-transforming growth factor beta receptor signaling pathway21947082
GO:0007179IMP-transforming growth factor beta receptor signaling pathway22344298
GO:0016579IDA-protein deubiquitination16005295
GO:0016579TAS-protein deubiquitination-
GO:0030509IDA-BMP signaling pathway21947082
GO:0035520IDA-monoubiquitinated protein deubiquitination21947082
GO:0035616IDA-histone H2B conserved C-terminal lysine deubiquitination24526689
GO:0060389IMP-pathway-restricted SMAD protein phosphorylation22344298
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
USP15ADSL10666719615732 Affinity Capture-MS
USP15ADSL11528319615732 Affinity Capture-MS
USP15ALDOA10672819615732 Affinity Capture-MS
USP15ALDOA11528319615732 Affinity Capture-MS
USP15CALML311528319615732 Affinity Capture-MS
USP15CALML310726119615732 Affinity Capture-MS
USP15CD4011528317353931 Affinity Capture-MS
USP15CD4010739617353931 Affinity Capture-MS
USP15CKB11528319615732 Affinity Capture-MS
USP15CKB10757219615732 Affinity Capture-MS
USP15CSTF111528319615732 Affinity Capture-MS
USP15CSTF110785919615732 Affinity Capture-MS
USP15DFFA11528317353931 Affinity Capture-MS
USP15DFFA10804017353931 Affinity Capture-MS
USP15FABP410846519615732 Affinity Capture-MS
USP15FABP411528319615732 Affinity Capture-MS
USP15KRT3111007919615732 Affinity Capture-MS
USP15KRT3111528319615732 Affinity Capture-MS
USP15KRT33B11008219615732 Affinity Capture-MS
USP15KRT33B11528319615732 Affinity Capture-MS
USP15KRT3411008319615732 Affinity Capture-MS
USP15KRT3411528319615732 Affinity Capture-MS
USP15KRT3511008419615732 Affinity Capture-MS
USP15KRT3511528319615732 Affinity Capture-MS
USP15KRT8111008519615732 Affinity Capture-MS
USP15KRT8111528319615732 Affinity Capture-MS
USP15KRT8511008919615732 Affinity Capture-MS
USP15KRT8511528319615732 Affinity Capture-MS
USP15LGALS711015419615732 Affinity Capture-MS
USP15LGALS711528319615732 Affinity Capture-MS
USP15MYH211528319615732 Affinity Capture-MS
USP15MYH211070519615732 Affinity Capture-MS
USP15MYH411528319615732 Affinity Capture-MS
USP15MYH411070719615732 Affinity Capture-MS
USP15PGAM211124519615732 Affinity Capture-MS
USP15PGAM211528319615732 Affinity Capture-MS
USP15PSMD711528319615732 Affinity Capture-Western
USP15PSMD711168519615732 Affinity Capture-Western
USP15PSMD1111528319615732 Affinity Capture-MS
USP15PSMD1111168919615732 Affinity Capture-MS
USP15UBC11316416005295 Reconstituted Complex
USP15UBC11528316005295 Reconstituted Complex
USP15UBE2G211317517353931 Affinity Capture-MS
USP15UBE2G211528317353931 Affinity Capture-MS
USP15USP1111386619615732 Affinity Capture-Western
USP15USP1111528319615732 Affinity Capture-Western
USP15SELENBP111528319615732 Affinity Capture-MS
USP15SELENBP111447219615732 Affinity Capture-MS
USP15PRPF411528319615732 Affinity Capture-MS
USP15PRPF411457619615732 Affinity Capture-MS
USP15PRPF311528319615732 Affinity Capture-MS
USP15PRPF311457719615732 Affinity Capture-MS
USP15SART311528319615732 Affinity Capture-MS
USP15SART311508219615732 Affinity Capture-MS
USP15RNF4011528319615732 Affinity Capture-MS
USP15RNF4011514919615732 Affinity Capture-MS
PHB2USP1511528317353931 Affinity Capture-MS
PHB2USP1511645917353931 Affinity Capture-MS
PPIHUSP1511528319615732 Affinity Capture-MS
PPIHUSP1511572819615732 Affinity Capture-MS
LSM6USP1511528319615732 Affinity Capture-MS
LSM6USP1511632819615732 Affinity Capture-MS
LRRC15USP1512628719615732 Affinity Capture-MS
LRRC15USP1511528319615732 Affinity Capture-MS
LSM4USP1511528319615732 Affinity Capture-MS
LSM4USP1511733619615732 Affinity Capture-MS
PRPF31USP1511528319615732 Affinity Capture-MS
PRPF31USP1511756319615732 Affinity Capture-MS
VSIG8USP1511528319615732 Affinity Capture-MS
VSIG8USP1513381319615732 Affinity Capture-MS
NAA38USP1511528319615732 Affinity Capture-MS
NAA38USP1511967919615732 Affinity Capture-MS
MEPCEUSP1511528319615732 Affinity Capture-MS
MEPCEUSP1512112219615732 Affinity Capture-MS
LSM2USP1511528319615732 Affinity Capture-MS
LSM2USP1512177819615732 Affinity Capture-MS
TUT1USP1512232519615732 Affinity Capture-MS
TUT1USP1511528319615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101857
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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